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Emerging biomarkers and targeted therapies in feline mammary carcinoma

2021-08-11Journal article Open access
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dc.contributor.authorGameiro, Andreia
dc.contributor.authorUrbano, Ana Catarina
dc.contributor.authorFerreira, Fernando
dc.date.accessioned2022-02-05T22:20:08Z
dc.date.available2022-02-05T22:20:08Z
dc.date.issued2021-08-11
dc.descriptionResearch Areas: Veterinary Sciencespt_PT
dc.description.abstractABSTRACT - : Feline mammary carcinoma (FMC) is a common aggressive malignancy with a low survival rate that lacks viable therapeutic options beyond mastectomy. Recently, increasing efforts have been made to understand the molecular mechanisms underlying FMC development, using the knowledge gained from studies on human breast cancer to discover new diagnostic and prognostic biomarkers, thus reinforcing the utility of the cat as a cancer model. In this article, we review the current knowledge on FMC pathogenesis, biomarkers, and prognosis factors and offer new insights into novel therapeutic options for HER2-positive and triple-negative FMC subtypes.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationGameiro A, Urbano AC, Ferreira F. 2021. Emerging biomarkers and targeted therapies in feline mammary carcinoma. Veterinary Sciences, 8(8):164. Doi: 10.3390/vetsci8080164pt_PT
dc.identifier.doi10.3390/vetsci8080164pt_PT
dc.identifier.eissn2306-7381
dc.identifier.urihttp://hdl.handle.net/10400.5/23404
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.relationCentre for Interdisciplinary Research in Animal Health
dc.relationDeveloping diagnostic tools for feline mammary carcinomas and improving chemotherapy based on HER2 and topoisometase status
dc.relation.publisherversionhttps://www.mdpi.com/2306-7381/8/8/164pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectFeline mammary carcinomapt_PT
dc.subjectBiomarkerspt_PT
dc.subjectFeline her2 mutationspt_PT
dc.subjectTargeted therapiespt_PT
dc.subjectComparative oncology modelpt_PT
dc.titleEmerging biomarkers and targeted therapies in feline mammary carcinomapt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleCentre for Interdisciplinary Research in Animal Health
oaire.awardTitleDeveloping diagnostic tools for feline mammary carcinomas and improving chemotherapy based on HER2 and topoisometase status
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/3599-PPCDT/PTDC%2FCVT-EPI%2F3638%2F2014/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F00276%2F2020/PT
oaire.awardURIinfo:eu-repo/grantAgreement/FCT//SFRH%2FBD%2F132260%2F2017/PT
oaire.citation.conferencePlaceBasel, Switzerlandpt_PT
oaire.citation.titleVeterinary Sciencespt_PT
oaire.citation.volumeVol.8(8):164pt_PT
oaire.fundingStream3599-PPCDT
oaire.fundingStream6817 - DCRRNI ID
person.familyNameGameiro
person.familyNameFernandes Urbano
person.familyNameFerreira
person.givenNameAndreia
person.givenNameAna Catarina
person.givenNameFernando António da Costa
person.identifier.ciencia-id2317-6BE3-E5F4
person.identifier.ciencia-idF81F-D7D4-57C5
person.identifier.orcid0000-0002-1602-3552
person.identifier.orcid0000-0001-5765-576X
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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