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Produtos naturais como alternativa terapêutica na doença de Parkinson
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Orientador(es)
Resumo(s)
A doença de Parkinson é uma doença neurodegenerativa complexa com sintomas quer motores quer não-motores que levam a um processo de perda neuronal no cérebro.
Existem várias factores de risco como a idade, a genética e o ambiente e vários mecanismos de neurodegeneração. De momento, só existe tratamento sintomático que não altera o processo degenerativo e tem alguns efeitos adversos. Por isso é muito importante a procura de novas terapêuticas.
Os produtos naturais são uma opção viável na Doença de Parkinson que demonstraram actuar por vários mecanismos e prevenir a doença de forma bastante eficaz. O estudo de plantas como Mucuna pruriens, Vicia faba, Banisteriopis caapi, família Piperaceae, Zingiber officinale roscoe, Gingko biloba, Salvia miltiorrhiza, Coffea sp., Nicotiana tabacum, Camellia sinensis, Curcuma longa e Panax ginseng revelaram que o seu consumo regular é excelente na prevenção da doença de Parkinson e que os efeitos benéficos obtidos são melhores aos da terapêutica actual.
Parkinson disease is a complex neurodegenerative disorder with both motor and nonmotor symptoms that lead to a process of neuronal loss in the brain. At present, only symptomatic treatment exists and nothing can be done to halt the degenerative process in the brain. There are risk factors such as aging, genetic susceptibility, and environmental factors and many neurodegenerative mechanisms. At the moment the treatment is symptomatic and do not halter the neurodegenerative process. So it is very important to search new therapies. Natural products are a good option in Parkinson disease that have activity throught several mechanisms and prevent the disease in a very effective way. The study of plants such as Mucuna pruriens, Vicia faba, Banisteriopis caapi, família Piperaceae, Zingiber officinale roscoe, Gingko biloba, Salvia miltiorrhiza, Coffea sp., Nicotiana tabacum, Camellia sinensis, Curcuma longa e Panax ginseng revealed that their regular consumption are excellent for DP prevention and that the effects are better than the actual therapy.
Parkinson disease is a complex neurodegenerative disorder with both motor and nonmotor symptoms that lead to a process of neuronal loss in the brain. At present, only symptomatic treatment exists and nothing can be done to halt the degenerative process in the brain. There are risk factors such as aging, genetic susceptibility, and environmental factors and many neurodegenerative mechanisms. At the moment the treatment is symptomatic and do not halter the neurodegenerative process. So it is very important to search new therapies. Natural products are a good option in Parkinson disease that have activity throught several mechanisms and prevent the disease in a very effective way. The study of plants such as Mucuna pruriens, Vicia faba, Banisteriopis caapi, família Piperaceae, Zingiber officinale roscoe, Gingko biloba, Salvia miltiorrhiza, Coffea sp., Nicotiana tabacum, Camellia sinensis, Curcuma longa e Panax ginseng revealed that their regular consumption are excellent for DP prevention and that the effects are better than the actual therapy.
Descrição
Trabalho Final de Mestrado Integrado, Ciências Farmacêuticas, Universidade de Lisboa, Faculdade de Farmácia, 2013
Palavras-chave
Mestrado Integrado - 2013