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Psychiatric disorders as predictors of epilepsy surgery outcome
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Orientador(es)
Resumo(s)
Objectives: Our aim was to determine if a history of a mental disorder predicts a worst neurological outcome for
patients undergoing epilepsy surgery.
Methods: We conducted an ambispective observational study including people with refractory epilepsy who
underwent resective surgery. Demographic, psychiatric, and neurological data were collected, before and one
year after surgery. Presurgical interviews included a psychiatric evaluation and the determination of prevalent
and lifetime psychiatric diagnosis. The one-year postsurgical outcome was classified according to the Engel Outcome Scale. Predictors of postsurgical Engel class were determined using an ordered logistic regression model.
Results: A lifetime history of any mental disorder was a significant predictor of a higher Engel Class (p = 0.017).
Conclusion: This study shows that psychiatric lifetime diagnoses are associated with worse surgical outcome and highlighted the importance of the inclusion of these diagnoses in the evaluation of the potential success of the surgery.
Descrição
© 2019 Elsevier Inc. All rights reserved
Palavras-chave
Refractory epilepsy Epilepsy surgery Outcome Psychiatric disorders
Contexto Educativo
Citação
Epilepsy Behav. 2019 Nov;100(Pt A):106513
Editora
Elsevier