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Respiratory failure in pulmonary hypertension patients

dc.contributor.authorGuia, Miguel Filipe
dc.contributor.authorPaula, Fernanda
dc.contributor.authorPinto, Paula
dc.contributor.authorFroes, Filipe
dc.date.accessioned2020-09-16T13:25:08Z
dc.date.available2020-09-16T13:25:08Z
dc.date.issued2020
dc.description© 2020 Published by Elsevier España, S.L.U. on behalf of Sociedade Portuguesa de Cardiologia. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).pt_PT
dc.description.abstractManagement of respiratory failure (RF) in pulmonary hypertension (PH) is a complex subject, since positive pressure ventilation (PPV) can reduce right ventricular (RV) output. During PPV there is an increase in intrathoracic pressure, increasing right atrial pressure. This leads to lower venous return and consequently to decreased RV preload and output. Furthermore, pulmonary vascular resistance (PVR), the main determinant of RV afterload, is directly affected by changes in lung volume, since when the lung is hyperinflated, alveolar distension occurs, leading to compression of the alveolar vessels. On the other hand, low lung volumes result in terminal airway collapse and hypoxic vasoconstriction, and parenchymal vessels also become more tortuous and predisposed to collapse.All the above factorstend to reduce left ventricular output, leading to systemic hypotension.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationRev Port Cardiol. 2020;39(9):551-552pt_PT
dc.identifier.doi10.1016/j.repc.2020.01.009pt_PT
dc.identifier.eissn2174-2030
dc.identifier.issn0870-2551
dc.identifier.urihttp://hdl.handle.net/10451/44381
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relation.publisherversionhttps://www.sciencedirect.com/journal/revista-portuguesa-de-cardiologiapt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.titleRespiratory failure in pulmonary hypertension patientspt_PT
dc.title.alternativeInsuficiência respiratória na hipertensão pulmonarpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage552pt_PT
oaire.citation.issue9pt_PT
oaire.citation.startPage551pt_PT
oaire.citation.titleRevista Portuguesa de Cardiologíapt_PT
oaire.citation.volume39pt_PT
person.familyNamePinto
person.familyNameFroes
person.givenNamePaula Maria Gonçalves
person.givenNameFilipe
person.identifier.ciencia-idF01D-6AFB-DFFD
person.identifier.ciencia-idC417-94B1-1A98
person.identifier.orcid0000-0003-2301-2752
person.identifier.orcid0000-0003-4135-6022
person.identifier.ridF-6607-2015
person.identifier.scopus-author-id24074744900
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication51c6d0a2-901f-49cc-b16d-08f96b6a4dd6
relation.isAuthorOfPublication3cd9c51d-f87b-47ab-b8b6-7e4f77d2ceb6
relation.isAuthorOfPublication.latestForDiscovery3cd9c51d-f87b-47ab-b8b6-7e4f77d2ceb6

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