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Publicação
May the right-side epileptogenic zone be a predictor of psychiatric comorbidity in people with refractory epilepsy?
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Orientador(es)
Resumo(s)
The aim of this study was to determine the rate and types of lifetime psychiatric disorders, as well as their predictors, in a sample of people with refractory epilepsy. Demographic, neurological, psychiatric and neuropsychological data, from people with refractory epilepsy, were registered at the pre-surgical interview. Linear regression was used to determine predictors. One hundred and ninety-one participants were included. Forty-six percent of our sample had at least one previous psychiatric diagnosis, most frequently depressive (64%), anxiety (10%), substance use (10%) and psychotic disorders (6%). Patients with a right-side epileptogenic zone had an increased risk for these disorders (OR 2.36; CI 1.22-4.56; p = 0.01). Specific epilepsy-related factors may raise the risk of developing a psychiatric disorder. Our study adds evidence to support a bidirectional relationship between epilepsy and mental health.
Descrição
© 2019 Informa UK Limited, trading as Taylor & Francis Group.
Palavras-chave
Refractory epilepsy Epileptogenic zone Laterality Psychiatric disorders
Contexto Educativo
Citação
Laterality, 2020, Vol. 25, no. 3, 275–284
Editora
Taylor & Francis Group