Publicação
Preserved CD4 T-cell telomere length during long-lasting HIV-2 infection --Manuscript Draft--
| dc.contributor.author | Tendeiro, R. | |
| dc.contributor.author | Albuquerque, A. S. | |
| dc.contributor.author | Foxall, Russell B. | |
| dc.contributor.author | Cavaleiro, R. | |
| dc.contributor.author | Soares, R. S. | |
| dc.contributor.author | Baptista, A. P. | |
| dc.contributor.author | Soares, M. V. | |
| dc.contributor.author | Gomes, P. | |
| dc.contributor.author | Sousa, A. E. | |
| dc.date.accessioned | 2015-06-17T14:02:47Z | |
| dc.date.available | 2015-06-17T14:02:47Z | |
| dc.date.issued | 2013 | |
| dc.description | © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins | eng |
| dc.description.abstract | HIV-2 infection features a much slower course than HIV-1 infection, often asymptomatic for over 20 years, without antiretroviral therapy (ART). Nevertheless, CD4 T cells progressively decline, in direct correlation with immune activation and cell cycling. We report, for the first time, preserved telomere length within naive and memory CD4 subsets in prolonged HIV-2 infection despite the increased CD4 turnover. | eng |
| dc.description.sponsorship | The study was supported by ANRS (French National Agency for research on AIDS and viral hepatitis) and by the European Community’s Seventh Framework Programme (FP7/2007–2013) under the project ‘Collaborative HIV and Anti-HIV Drug Resistance Network (CHAIN)’ (grant no. 223131). | eng |
| dc.identifier.citation | AIDS 2013, 27:289–295 | por |
| dc.identifier.issn | 0269-9370 | |
| dc.identifier.uri | http://journals.lww.com/aidsonline/Fulltext/2013/01140/Preserved_CD4_T_cell_telomere_length_during.19.aspx | |
| dc.identifier.uri | http://dx.doi.org/10.1097/QAD.0b013e32835ab234 | |
| dc.identifier.uri | http://hdl.handle.net/10451/18306 | |
| dc.language.iso | eng | por |
| dc.peerreviewed | yes | por |
| dc.publisher | Lippincott, Williams & Wilkins | eng |
| dc.relation.publisherversion | The definitive version is available at http://journals.lww.com/pages/default.aspx | eng |
| dc.title | Preserved CD4 T-cell telomere length during long-lasting HIV-2 infection --Manuscript Draft-- | eng |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.title | AIDS: Official Journal of the International Aids Society | eng |
| rcaap.rights | closedAccess | por |
| rcaap.type | article | por |