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High sensitivity troponins: from the acute setting to the general population
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Orientador(es)
Resumo(s)
Troponins are proteins essential for the contraction of the myocardium and currently cardiac troponin I and cardiac troponin T are used as blood biomarkers to assess myocardial injury. Since 2000, with the Joint European Society of Cardiology/American College of Cardiology Committee for the redefinition of myocardial
infarction (MI) consensus document, troponins are formally used as biomarkers for MI diagnosis. The diagnostic advantages of troponins in terms of sensitivity and specificity over other biomarkers, such as creatine kinase (CK), including the MB isoform measurement, led to the adoption of troponins as preferred biomarkers over time. The current universal definition of MI (fourth version) focuses on high sensitivity troponins as the gold standard for the biomarker criterion for myocardial infarction and as a central criterion, in addition to clinical, ECG, cardiac imaging, coronary angiography or autopsy findings suggestive of MI.
Descrição
© 2022 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.
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Contexto Educativo
Citação
Eur J Intern Med. 2022 Mar 5;S0953-6205(22)00096-6
Editora
Elsevier