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O impacto da depressão na doença coronária : uma revisão narrativa
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Objetivo: Este trabalho tem como objetivo perceber qual o impacto que a perturbação depressiva pode ter na doença coronária, tentando estabelecer uma conexão fisiopatológica e comportamental entre as duas. Metodologia: Foi realizada uma pesquisa dos conceitos depression, antidepressants, emotional stress e coronary artery disease nas bases de dados Google Scholar, PubMed, Cochrane e SciLo. Foram selecionados os artigos em língua inglesa e posteriormente aplicados os critérios de seleção previamente definidos. Resultados: De um total de 186 artigos foram selecionados 19. Várias revisões e estudos demonstraram que existem mecanismos fisiopatológicos propostos que podem explicar a ligação entre a perturbação depressiva e a doença coronária, demonstrando ainda o impacto deste quadro psiquiátrico na mesma, tanto a nível da sua manutenção, como da terapêutica e do prognóstico destes doentes. Conclusão: A perturbação depressiva tem um claro impacto na progressão da doença coronária, no tratamento e no prognóstico da mesma, sendo, por isso, de extrema importância recorrermos a uma identificação atempada, seguida de uma gestão clínica cuidada e dirigida, de forma a melhorarmos o outcome e a qualidade de vida destes doentes.
Objective: This thesis has as its main goal to understand the impact of depressive disorder on coronary artery disease, trying to establish a pathophysiologic and behavioral connection between the two. Methodology: A research was carried out on the concepts of depression, antidepressants, emotional stress and coronary artery disease in the Google Scholar, PubMed, Cochrane and SciLo databases. Articles in English were selected and subsequently applied the previously defined selection criteria. Results: From a total of 186 articles, 19 were selected. Several reviews and studies have shown that there are some proposed pathophysiologic mechanisms that may explain the link between the depressive disorders and the coronary artery diseases, further demonstrating the impact of these psychiatric conditions on the latter, both in terms of maintenance, therapy and prognosis of these patients. Conclusion: The depressive disorder have a clear impact in the maintenance of coronary artery disease, in the therapy and in its prognosis, being, therefore, of extremely importance that we carry out a timely identification, followed by a careful and directed clinical management, in order to improve the outcome, the life expectancy and quality of life of these patients.
Objective: This thesis has as its main goal to understand the impact of depressive disorder on coronary artery disease, trying to establish a pathophysiologic and behavioral connection between the two. Methodology: A research was carried out on the concepts of depression, antidepressants, emotional stress and coronary artery disease in the Google Scholar, PubMed, Cochrane and SciLo databases. Articles in English were selected and subsequently applied the previously defined selection criteria. Results: From a total of 186 articles, 19 were selected. Several reviews and studies have shown that there are some proposed pathophysiologic mechanisms that may explain the link between the depressive disorders and the coronary artery diseases, further demonstrating the impact of these psychiatric conditions on the latter, both in terms of maintenance, therapy and prognosis of these patients. Conclusion: The depressive disorder have a clear impact in the maintenance of coronary artery disease, in the therapy and in its prognosis, being, therefore, of extremely importance that we carry out a timely identification, followed by a careful and directed clinical management, in order to improve the outcome, the life expectancy and quality of life of these patients.
Descrição
Trabalho Final do Curso de Mestrado Integrado em Medicina, Faculdade de Medicina, Universidade de Lisboa, 2023
Palavras-chave
Depressão Antidepressivos Stress emocional Doença arterial coronária Psiquiatria Psicologia médica