Logo do repositório
 
Publicação

Frequency of dementia in Parkinson's disease: a systematic review and meta-analysis

2022Artigo científico Acesso restrito
Ver registo simples
dc.contributor.authorSeveriano e Sousa, Catarina
dc.contributor.authorAlarcão, Joana
dc.contributor.authorMartins, Isabel Pavão
dc.contributor.authorFerreira, Joaquim J
dc.date.accessioned2022-01-25T14:28:50Z
dc.date.available2022-01-25T14:28:50Z
dc.date.issued2022
dc.description© 2021 Elsevier B.V. All rights reserved.pt_PT
dc.description.abstractBackground: There is a considerable variation in the reported frequency of dementia in Parkinson's disease (PDD). The aim of this study was to evaluate the frequency of PDD reported in published studies and to examine the different methodological, clinical, and demographic factors that may contribute to this variation. Methods: We conducted a systematic review, searching EMBASE and MEDLINE databases for relevant articles on PDD frequency published before May 2019. A global estimation of PDD was calculated. Different subgroup analyses were performed for methodological, clinical, and demographic characteristics. Meta-regression was also conducted to identify any significant differences within the subgroups. Results: We included 295 studies. The global pooled dementia frequency was 26.3%. These estimations varied according to methodological (14%-55%), clinical (18%-46%), and demographic (21%-43%) variables. The declared primary objective of the studies (to study PDD), the follow-up length (≥7 years), the age of the participants (≥75 years), Parkinson's disease (PD) duration (>10 years), and the Hoehn & Yahr (H&Y) stage (>3) were important factors affecting reported dementia frequency. Conclusions: This systematic review found that approximately one-quarter of the PD patients were diagnosed with PDD. Dementia frequency varied according to methodological, clinical and demographic variables. We cannot examine PDD frequency without considering all these variables that have an impact on it.pt_PT
dc.description.sponsorshipThis work was supported by a Doctoral Fellowship from Fundação para a Ciência e Tecnologia, Portugal [SFRH/BD/139853/2018], which was assigned to Catarina Severiano e Sousa.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationJ Neurol Sci. 2022 Jan 15;432:120077pt_PT
dc.identifier.doi10.1016/j.jns.2021.120077pt_PT
dc.identifier.eissn1878-5883
dc.identifier.issn0022-510X
dc.identifier.urihttp://hdl.handle.net/10451/50979
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relationCognitive Disorders in Late-Stage Parkinson´s Disease
dc.relation.publisherversionhttps://www.sciencedirect.com/journal/journal-of-the-neurological-sciencespt_PT
dc.subjectDementia frequencypt_PT
dc.subjectParkinson's diseasept_PT
dc.subjectSystematic reviewpt_PT
dc.titleFrequency of dementia in Parkinson's disease: a systematic review and meta-analysispt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardNumberSFRH/BD/139853/2018
oaire.awardTitleCognitive Disorders in Late-Stage Parkinson´s Disease
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/OE/SFRH%2FBD%2F139853%2F2018/PT
oaire.citation.titleJournal of the Neurological Sciencespt_PT
oaire.fundingStreamOE
person.familyNamePavão Martins
person.familyNameFerreira
person.givenNameIsabel
person.givenNameJoaquim J
person.identifier18561
person.identifier1624753
person.identifier.ciencia-id4D1D-4040-BE76
person.identifier.ciencia-id7D15-5CD6-6159
person.identifier.orcid0000-0002-9611-7400
person.identifier.orcid0000-0003-3950-5113
person.identifier.scopus-author-id7103152782
person.identifier.scopus-author-id7403252466
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationd134f8f9-be2a-4990-b8ec-3159ff3c51f2
relation.isAuthorOfPublication54d84fe7-2cbd-4ddc-bce2-0ff2bd7c4cc9
relation.isAuthorOfPublication.latestForDiscovery54d84fe7-2cbd-4ddc-bce2-0ff2bd7c4cc9
relation.isProjectOfPublicationd7ccf607-1bbd-4530-a910-40a40b6c5ad0
relation.isProjectOfPublication.latestForDiscoveryd7ccf607-1bbd-4530-a910-40a40b6c5ad0

Ficheiros

Principais
A mostrar 1 - 1 de 1
Miniatura indisponível
Nome:
Dementia_Parkinson.pdf
Tamanho:
1.01 MB
Formato:
Adobe Portable Document Format
Ver/Abrir

Coleções

FM-CEMBE-Artigos em Revistas Internacionais
FM - Artigos em Revistas Internacionais
IMM - Artigos em Revistas Internacionais