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Candidíase invasiva em doentes Covid-19 : revisão dos casos na literatura
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Os doentes com Covid 19 (do inglês, Coronavirus Disease 2019) têm sido um foco de estudo e investigação mundial nos últimos 2 anos. De entre os fatores identificados que contribuem para a morbilidade e mortalidade desta população, as infeções secundárias apresentam um papel importante no desfecho associado a estes doentes.
De entre estas infeções, a Candidíase Invasiva tem sido identificada como uma complicação importante. Com taxas de mortalidade elevadas, torna-se importante estudar esta população.
Este trabalho final de mestrado irá incidir sobre a Candidíase Invasiva em doentes com Covid-19. Apresenta-se uma revisão dos casos reportados na literatura e discute-se os mesmos na tentativa de melhor conhecer esta problemática.
Observou-se uma incidência de Candidíase Invasiva e mortalidade elevadas nos doentes com Covid-19. Os estudos que comparam doentes com e sem a doença mostram que os doentes com Covid-19 têm taxas de incidência e mortalidade mais altas.
Os dados compilados permitem gerar hipóteses acerca desta população que poderão servir de base para estudos futuros.
Coronavirus Disease 2019 (COVID-19) is a disease that has seen worldwide representation. Among the factors identified that contribute to increased morbity and mortality in the population affected by this disease, secondary infections pose as an important threat to the outcome of these patients. One of these infections, Invasive Candidiasis, has been identified as an important complication. It’s high mortality rates make it important to study this population. This master’s thesis will focus on Invasive Candidiasis in Covid-19 patients. Data regarding the cases described in the literature will be revised and discussed to better understand this problematic. We found a greater incidence and mortality associated with Invasive Candidiasis occurring in Covid-19 patients. Studies that compare patients with and without the disease show that Covid-19 patients have higher incidence and mortality rates. The data shown enables the generation of hypothesis that could guide future research in this area.
Coronavirus Disease 2019 (COVID-19) is a disease that has seen worldwide representation. Among the factors identified that contribute to increased morbity and mortality in the population affected by this disease, secondary infections pose as an important threat to the outcome of these patients. One of these infections, Invasive Candidiasis, has been identified as an important complication. It’s high mortality rates make it important to study this population. This master’s thesis will focus on Invasive Candidiasis in Covid-19 patients. Data regarding the cases described in the literature will be revised and discussed to better understand this problematic. We found a greater incidence and mortality associated with Invasive Candidiasis occurring in Covid-19 patients. Studies that compare patients with and without the disease show that Covid-19 patients have higher incidence and mortality rates. The data shown enables the generation of hypothesis that could guide future research in this area.
Descrição
Trabalho Final do Curso de Mestrado Integrado em Medicina, Faculdade de Medicina, Universidade de Lisboa, 2022
Palavras-chave
COVID-19 SARS-CoV-2 Candidíase invasiva Candidémia Doenças fúngicas invasivas Doenças transmissíveis