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The burden of atherosclerosis in Portugal

2020Journal article Open access
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dc.contributor.authorCosta, João
dc.contributor.authorAlarcão, Joana
dc.contributor.authorAraujo, Francisco
dc.contributor.authorAscenção, Raquel
dc.contributor.authorCaldeira, Daniel
dc.contributor.authorFiorentino, Francesca
dc.contributor.authorGil, Victor
dc.contributor.authorGouveia, Miguel
dc.contributor.authorLourenço, Francisco
dc.contributor.authorMello e Silva, Alberto
dc.contributor.authorSampaio, Filipa
dc.contributor.authorCarneiro, António Vaz
dc.contributor.authorBorges, Margarida
dc.date.accessioned2021-01-08T14:31:15Z
dc.date.available2021-01-08T14:31:15Z
dc.date.issued2020
dc.description© The Author(s) 2020. Published by Oxford University Press on behalf of the European Society of Cardiology. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contactjournals.permissions@oup.compt_PT
dc.description.abstractAims: This paper sought to estimate the burden of disease attributable to atherosclerosis in mainland Portugal in 2016. Methods and results: The burden of atherosclerosis was measured in disability-adjusted life years (DALY) following the latest 2010 Global Burden of Disease (GBD) methodology. DALYs were estimated as the sum of years of life lost (YLL) with years lived with disability (YLD). The following clinical manifestations of atherosclerosis were included: ischemic heart disease (IHD) (including acute myocardial infarction (AMI), stable angina, and ischemic heart failure (IHF)), ischemic cerebrovascular disease (ICVD) and peripheral arterial disease (PAD). YLL were estimated based on all-cause mortality data for the Portuguese population and mortality due to IHD, ICVD and PAD for the year 2016 sourced from national statistics. Standard life expectancy was sourced from the GBD study. YLD corresponded to the product of the number of prevalent cases by an average disability weight (DW) for all possible combinations of disease. Prevalence data for the different clinical manifestations of atherosclerosis were sourced from epidemiological studies. DW were sourced from the published literature. In 2016, 15,123 deaths were attributable to atherosclerosis, which corresponded to 14.3% of overall mortality in mainland Portugal. DALYs totaled 260,943, 75% due to premature death (196,438 YLL) and 25% due to disability (64,505 YLD). Conclusion: Atherosclerosis entails a high disease burden to society. A large part of this burden would be avoidable if evidence-based effective and cost-effective interventions targeting known risk factors, from prevention to treatment, were implemented.pt_PT
dc.description.sponsorshipThis study was funded by Bayer Portugal, Lda. Funding was independent of the study outcomes.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationEuropean Heart Journal - Quality of Care and Clinical Outcomes (2020) 0, 1–9, qcaa060pt_PT
dc.identifier.doi10.1093/ehjqcco/qcaa060pt_PT
dc.identifier.eissn2058-1742
dc.identifier.issn2058-5225
dc.identifier.urihttp://hdl.handle.net/10451/45713
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherOxford University Presspt_PT
dc.relation.publisherversionhttps://academic.oup.com/ehjqccopt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/pt_PT
dc.subjectAtherosclerosispt_PT
dc.subjectBurden of diseasept_PT
dc.subjectDALYspt_PT
dc.subjectMorbiditypt_PT
dc.subjectMortalitypt_PT
dc.subjectPortugalpt_PT
dc.titleThe burden of atherosclerosis in Portugalpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleEuropean Heart Journal - Quality of Care & Clinical Outcomespt_PT
person.familyNameCosta
person.familyNameAraujo
person.familyNameAscenção
person.familyNameCaldeira
person.familyNameGil
person.familyNameLourenço
person.familyNameRibeiro Pimenta Sampaio
person.familyNameVaz Carneiro
person.familyNameBorges
person.givenNameJoão
person.givenNameFrancisco
person.givenNameRaquel
person.givenNameDaniel
person.givenNameVictor
person.givenNameFrancisco
person.givenNameFilipa de Jesus
person.givenNameAntónio
person.givenNameMargarida
person.identifier480560
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person.identifier.orcid0000-0002-5831-4921
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person.identifier.orcid0000-0003-4014-5450
person.identifier.orcid0000-0001-9996-5483
person.identifier.orcid0000-0002-5540-9853
person.identifier.orcid0000-0002-2783-0544
person.identifier.orcid0000-0002-8563-6846
person.identifier.ridL-8026-2013
person.identifier.scopus-author-id55499748300
person.identifier.scopus-author-id35515214000
person.identifier.scopus-author-id36623384200
person.identifier.scopus-author-id57201233134
person.identifier.scopus-author-id7006837792
person.identifier.scopus-author-id7102828573
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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