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Metacarpal cortical bone loss and osteoporotic fractures in the Coimbra Identified Skeletal Collection

dc.contributor.authorCurate, Francisco
dc.contributor.authorPerinha, Andreia
dc.contributor.authorSilva, Ana Maria
dc.contributor.authorCunha, Eugénia
dc.contributor.authorUmbelino, Cláudia
dc.contributor.authorNogueira, Catarina
dc.date.accessioned2020-04-21T08:02:18Z
dc.date.available2020-04-21T08:02:18Z
dc.date.issued2019
dc.description.abstractThere has been considerable progress in recent years in our understanding of the patterns of cortical bone loss in the second metacarpal in archeological skeletal samples. Nevertheless, cortical data from reference skeletal collections are insufficient, and the possible connection of metacarpal cortical parameters with osteoporotic fractures has not been thoroughly addressed. As such, this article aims to identify and explain sex‐specific and age‐associated metacarpal cortical bone loss in a large sample (N = 302; females: 154/males: 148) from the Coimbra Identified Skeletal Collection. Another objective is to evaluate the association of cortical and demographic features with osteoporotic fractures. Age‐related endocortical bone loss is significant in women but not evident in men. Periosteal accretion of the bone is absent in both sexes. Overall, there is a net loss of the cortical bone in women, whereas cortical bone strength seems to be preserved in men. The prevalence of osteoporotic fractures is similar in both sexes, with age at death significantly influencing the probability of exhibiting a fracture. Metacarpal cortical index does not seem to be an independent risk factor for osteoporotic fractures in this sample.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationCurate, F., Perinha, A., Silva, A. M., Cunha, E., Umbelino, C., & Nogueira, C. (2019). Metacarpal cortical bone loss and osteoporotic fractures in the Coimbra Identified Skeletal Collection. International Journal of Osteoarchaeology, 29(1) 73-81. doi: 10.1002/oa.2717pt_PT
dc.identifier.doi10.1002/oa.2717pt_PT
dc.identifier.issn1047-482X
dc.identifier.issn1099-1212
dc.identifier.urihttp://hdl.handle.net/10451/42982
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherWileypt_PT
dc.relation.publisherversionhttps://onlinelibrary.wiley.com/doi/full/10.1002/oa.2717pt_PT
dc.subjectBone fragilitypt_PT
dc.subjectFragility fracturespt_PT
dc.subjectIdentified reference skeletal collectionspt_PT
dc.subjectOsteoporosispt_PT
dc.titleMetacarpal cortical bone loss and osteoporotic fractures in the Coimbra Identified Skeletal Collectionpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBPD%2F74015%2F2010/PT
oaire.citation.endPage81pt_PT
oaire.citation.startPage73pt_PT
oaire.citation.titleInternational Journal of Osteoarchaeologypt_PT
oaire.citation.volume29(1)pt_PT
oaire.fundingStreamSFRH
person.familyNameSilva
person.givenNameAna Maria
person.identifier.ciencia-idF21D-4659-29AB
person.identifier.orcid0000-0002-1912-6581
person.identifier.ridE-6281-2015
person.identifier.scopus-author-id55939389400
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsclosedAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication2bd9c836-5465-4034-afd9-f3d50381488c
relation.isAuthorOfPublication.latestForDiscovery2bd9c836-5465-4034-afd9-f3d50381488c
relation.isProjectOfPublicatione82b0903-20b5-41f1-8f2b-c27c19b0e952
relation.isProjectOfPublication.latestForDiscoverye82b0903-20b5-41f1-8f2b-c27c19b0e952

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