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The global NAFLD policy review and preparedness index: are countries ready to address this silent public health challenge?

2022Artigo científico Acesso aberto
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dc.contributor.authorLazarus, Jeffrey V.
dc.contributor.authorMark, Henry E.
dc.contributor.authorVillota-Rivas, Marcela
dc.contributor.authorPalayew, Adam
dc.contributor.authorCarrieri, Patrizia
dc.contributor.authorColombo, Massimo
dc.contributor.authorEkstedt, Mattias
dc.contributor.authorEsmat, Gamal
dc.contributor.authorGeorge, Jacob
dc.contributor.authorMarchesini, Giulio
dc.contributor.authorNovak, Katja
dc.contributor.authorOcama, Ponsiano
dc.contributor.authorRatziu, Vlad
dc.contributor.authorRazavi, Homie
dc.contributor.authorRomero-Gómez, Manuel
dc.contributor.authorSilva, Marcelo
dc.contributor.authorSpearman, C. Wendy
dc.contributor.authorTacke, Frank
dc.contributor.authorTsochatzis, Emmanuel A.
dc.contributor.authorYilmaz, Yusuf
dc.contributor.authorYounossi, Zobair M.
dc.contributor.authorWong, Vincent W.-S.
dc.contributor.authorZelber-Sagi, Shira
dc.contributor.authorCortez-Pinto, Helena
dc.contributor.authorAnstee, Quentin M.
dc.contributor.authorRouabhia, Samir
dc.contributor.authorGhazinyan, Hasmik
dc.contributor.authorIskandar, Natacha Jreige
dc.contributor.authorTrauner, Michael
dc.contributor.authorAghayeva, Gulnara
dc.contributor.authorCarter, Flloyd
dc.contributor.authorSridharan, Kannan
dc.contributor.authorAl Mahtab, Mamun
dc.contributor.authorFrancque, Sven
dc.contributor.authorKodjoh, Nicolas
dc.contributor.authorCamacho, Ruben Muñoz
dc.contributor.authorAnderson, Motswedi
dc.contributor.authorMarques Souza de Oliveira, Claudia Pinto
dc.contributor.authorMateva, Lyudmila
dc.contributor.authorSerme, Abdel Karim
dc.contributor.authorSoares Martins, Antonieta A.
dc.contributor.authorSwain, Mark G.
dc.contributor.authorKomas, Narcisse Patrice
dc.contributor.authorZheng, Ming-Hua
dc.contributor.authorJaramillo, Patricio Lopez
dc.contributor.authorMurillo, Omar Alfaro
dc.contributor.authorMikolasevic, Ivana
dc.contributor.authorVounou, Emmelia
dc.contributor.authorBrůha, Radan
dc.contributor.authorNlombi, Charles Mbendi
dc.contributor.authorThiele, Maja
dc.contributor.authorPerez, Marlene
dc.contributor.authorSuárez M, Juan José
dc.contributor.authorWaked, Imam
dc.contributor.authorSalupere, Riina
dc.contributor.authorDesalegn, Hailemichael
dc.contributor.authorYki-Järvinen, Hannele
dc.contributor.authorTsertsvadze, Tengiz
dc.contributor.authorSharvadze, Lali
dc.contributor.authorButsashvili, Maia
dc.contributor.authorAwuku, Yaw Asante
dc.contributor.authorPapatheodoridis, Georgios
dc.contributor.authorHunyady, Bela
dc.contributor.authorBjornsson, Einar Stefan
dc.contributor.authorDuseja, Ajay
dc.contributor.authorLesmana, Cosmas Rinaldi A.
dc.contributor.authorMalekzadeh, Reza
dc.contributor.authorNorris, Suzanne
dc.contributor.authorKoike, Kazuhiko
dc.contributor.authorNersesov, Alexander V.
dc.contributor.authorOchwoto, Missiani
dc.contributor.authorJamal, Mohammad
dc.contributor.authorSaparbu, Tobokalova
dc.contributor.authorTolmane, Ieva
dc.contributor.authorSayegh, Raymond
dc.contributor.authorSheriff, Dhastagir Sultan
dc.contributor.authorValantinas, Jonas
dc.contributor.authorWeber, Joseph
dc.contributor.authorShawa, Isaac Thom
dc.contributor.authorTan, Soek-Siam
dc.contributor.authorMartínez Vázquez, Sophia E.
dc.contributor.authorBaatarkhuu, Oidov
dc.contributor.authorLkhagvaa, Undram
dc.contributor.authorJadamba, Tsolmon
dc.contributor.authorMohammed, Tahiri
dc.contributor.authorSudhamshu, K.C
dc.contributor.authorCoppell, Kirsten
dc.contributor.authorOnyekwere, Charles
dc.contributor.authorNikolova, Dafina
dc.contributor.authorVesterhus, Mette
dc.contributor.authorAl-Naamani, Khalid
dc.contributor.authorHamid, Saeed
dc.contributor.authorMéndez, Juan Paredes
dc.contributor.authorCabrera Cabrejos, María Cecilia
dc.contributor.authorFlisiak, Robert
dc.contributor.authorTorres, Esther A.
dc.contributor.authorTaheri, Shahrad
dc.contributor.authorSung, Ki-Chul
dc.contributor.authorAdela, Turcanu
dc.contributor.authorGheorghe, Liana
dc.contributor.authorSanai, Faisal M.
dc.contributor.authorMilovanovic, Tamara
dc.contributor.authorBee Goh, George Boon
dc.contributor.authorRac, Marek
dc.contributor.authorDassanayake, Anuradha
dc.contributor.authorOsama, Shahinaz Bedri
dc.contributor.authorElsanousi, M.
dc.contributor.authorDufour, Jean-François
dc.contributor.authorKao, Jia-Horng
dc.contributor.authorSaidi, Dilshod
dc.contributor.authorTreeprasertsuk, Sombat
dc.contributor.authorKoek, Ger
dc.contributor.authorLabidi, Asma
dc.contributor.authorSkrypnyk, Igor
dc.contributor.authorAlKhatry, Maryam Salem
dc.contributor.authorSadirova, Shakhlo
dc.contributor.authorBakieva, Shokhista
dc.contributor.authorSinkala, Edford
dc.date.accessioned2022-11-04T16:30:37Z
dc.date.available2022-11-04T16:30:37Z
dc.date.issued2022
dc.description© 2021 The Author(s). Published by Elsevier B.V. on behalf of European Association for the Study of the Liver. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).pt_PT
dc.description.abstractBackground & aims: Non-alcoholic fatty liver disease (NAFLD) is a highly prevalent, yet largely underappreciated liver condition which is closely associated with obesity and metabolic disease. Despite affecting an estimated 1 in 4 adults globally, NAFLD is largely absent on national and global health agendas. Methods: We collected data from 102 countries, accounting for 86% of the world population, on NAFLD policies, guidelines, civil society engagement, clinical management, and epidemiologic data. A preparedness index was developed by coding questions into 6 domains (policies, guidelines, civil awareness, epidemiology and data, NAFLD detection, and NAFLD care management) and categorising the responses as high, medium, and low; a multiple correspondence analysis was then applied. Results: The highest scoring countries were India (42.7) and the United Kingdom (40.0), with 32 countries (31%) scoring zero out of 100. For 5 of the domains a minority of countries were categorised as high-level while the majority were categorised as low-level. No country had a national or sub-national strategy for NAFLD and <2% of the different strategies for related conditions included any mention of NAFLD. National NAFLD clinical guidelines were present in only 32 countries. Conclusions: Although NAFLD is a pressing public health problem, no country was found to be well prepared to address it. There is a pressing need for strategies to address NAFLD at national and global levels. Lay summary: Around a third of the countries scored a zero on the NAFLD policy preparedness index, with no country scoring over 50/100. Although NAFLD is a pressing public health problem, a comprehensive public health response is lacking in all 102 countries. Policies and strategies to address NAFLD at the national and global levels are urgently needed.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationJ Hepatol. 2022 Apr;76(4):771-780pt_PT
dc.identifier.doi10.1016/j.jhep.2021.10.025pt_PT
dc.identifier.eissn1600-0641
dc.identifier.issn0168-8278
dc.identifier.urihttp://hdl.handle.net/10451/54960
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relation.publisherversionhttps://www.sciencedirect.com/journal/journal-of-hepatologypt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectNon-alcoholic fatty liver disease (NAFLD)pt_PT
dc.subjectGlobal public healthpt_PT
dc.subjectHealth policypt_PT
dc.subjectLiver healthpt_PT
dc.subjectMultiple correspondence analysispt_PT
dc.subjectNon-alcoholic steatohepatitis (NASH)pt_PT
dc.subjectPolicy preparednesspt_PT
dc.titleThe global NAFLD policy review and preparedness index: are countries ready to address this silent public health challenge?pt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage780pt_PT
oaire.citation.issue4pt_PT
oaire.citation.startPage771pt_PT
oaire.citation.titleJournal of Hepatologypt_PT
oaire.citation.volume76pt_PT
person.familyNameCortez-Pinto
person.givenNameHelena
person.identifier.ciencia-idA01C-0511-C986
person.identifier.orcid0000-0002-8537-8744
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication91fdb4b3-d491-4e67-94ff-dcf5013fa1a7
relation.isAuthorOfPublication.latestForDiscovery91fdb4b3-d491-4e67-94ff-dcf5013fa1a7

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