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Development of a Monte Carlo Framework to Simulate 3D-Printed Plastics in Proton Therapy Beams

datacite.subject.fosDepartamento de Físicapt_PT
dc.contributor.advisorVeiga, Catarina
dc.contributor.advisorFerreira, Brígida da Costa
dc.contributor.authorReis, Cláudia Andreia Caetano
dc.date.accessioned2024-06-27T14:16:35Z
dc.date.available2024-06-27T14:16:35Z
dc.date.issued2024
dc.date.submitted2024
dc.descriptionTese de mestrado, Engenharia Biomédica e Biofísica , 2024, Universidade de Lisboa, Faculdade de Ciênciaspt_PT
dc.description.abstractQuality assurance procedures are extremely important to guarantee proper dose delivery during radiation treatments and 3D-printed phantoms have an important role, especially in proton therapy due to the lack of commercially available options. Different printing parameters can be used to modify the radiological properties of tissue-equivalent 3D-printed plastics used in phantoms and, thus, more accurately mimic the heterogeneities of human tissues. Radiation simulations can be used to faster investigate the impact of such printing parameters. Therefore, this Master’s dissertation aimed to develop and validate a Monte Carlo simulation environment that allowed for the accurate estimation of the radiological properties of 3D-printed plastics with different 3D-printing parameters, namely printing direction, infill patterns and infill percentage. Fourteen plastic slabs were 3D-printed using Fused Deposition Modeling and included two patternless slabs and two slabs with 20%, 50% and 80% infill for both Full Honeycomb and Grid patterns, each set of two slabs with one horizontally printed and one vertically printed. Single-shot Bragg peak measurements were performed and a simulation environment recreating the experimental environment was created in the Monte Carlo simulation software, GATE. Two geometry approaches for the 3D-printed slabs were investigated as well as their respective materials. The research showed that GATE presents some limitations when generating volumetric geometries, however when simulating voxelised geometries no limitations nor incorrect simulation outputs seem to be present. The mixed material of PLA and air was shown to better match the patternless slabs contrary to 100% PLA. Horizontally printed simulated slabs presented a two-peak shape curves which are due to a perfect alignment of the simulation setup, contrary to the experimental environment. A gap tune was needed for the vertically printed simulated slabs with Grid pattern. A maximum R80/WET absolute difference to experimental measurements of 1.1 mm was found for vertically printed slabs.pt_PT
dc.identifier.tid203684729
dc.identifier.urihttp://hdl.handle.net/10451/65151
dc.language.isoengpt_PT
dc.subjectSimulações Monte Carlopt_PT
dc.subjectImpressão 3Dpt_PT
dc.subjectTerapia com Protõespt_PT
dc.subjectTeses de mestrado - 2024pt_PT
dc.titleDevelopment of a Monte Carlo Framework to Simulate 3D-Printed Plastics in Proton Therapy Beamspt_PT
dc.typemaster thesis
dspace.entity.typePublication
rcaap.rightsopenAccesspt_PT
rcaap.typemasterThesispt_PT
thesis.degree.nameTese de mestrado em Engenharia Biomédica e Biofísicapt_PT

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