Publicação
Genetic characterisation of the ethambutol resistance-determining region in Mycobacterium tuberculosis
| dc.contributor.author | Perdigao, Joao | |
| dc.contributor.author | Macedo, Rita | |
| dc.contributor.author | Ribeiro, Ana | |
| dc.contributor.author | Brum, Laura | |
| dc.contributor.author | Portugal, Isabel | |
| dc.date.accessioned | 2015-12-30T10:18:21Z | |
| dc.date.available | 2015-12-30T10:18:21Z | |
| dc.date.issued | 2009 | |
| dc.description.abstract | Ethambutol (EMB) is a first-line antitubercular drug that inhibits arabinogalactan and lipoarabinomannan biosynthesis. Resistance to EMB has traditionally been associated with embB mutations, especially in the Met306 codon. In this study, the region encom. - Fundacao Calouste Gulbenkian, Lisbon, Portugal [FCG 001013]. - Funding: This work was supported by Fundacao Calouste Gulbenkian, Lisbon, Portugal (grant FCG 001013). | |
| dc.format | application/pdf | |
| dc.identifier.citation | INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS. - Vol. 33, n. 4 (APR 2009), p. 334-338 | |
| dc.identifier.doi | http://dx.doi.org/10.1016/j.ijantimicag.2008.09.021 | |
| dc.identifier.issn | 0924-8579 | |
| dc.identifier.uri | http://hdl.handle.net/10451/21542 | |
| dc.language.iso | eng | |
| dc.publisher | ELSEVIER SCIENCE BV | |
| dc.subject | Infectious Diseases | |
| dc.subject | Microbiology | |
| dc.subject | Pharmacology & Pharmacy | |
| dc.title | Genetic characterisation of the ethambutol resistance-determining region in Mycobacterium tuberculosis | |
| dc.title | prevalence and significance of embB306 mutations | |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 338 | por |
| oaire.citation.startPage | 334 | por |
| oaire.citation.title | INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS | por |
| oaire.citation.volume | Vol. 33 | por |
| rcaap.rights | restrictedAccess | |
| rcaap.type | article |