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The current and future burden of heart failure in Portugal

dc.contributor.authorGouveia, Miguel
dc.contributor.authorAscenção, Raquel
dc.contributor.authorFiorentino, Francesca
dc.contributor.authorCosta, João
dc.contributor.authorCaldeira, Daniel
dc.contributor.authorBroeiro-Gonçalves, Paula
dc.contributor.authorFonseca, Candida
dc.contributor.authorBorges, Margarida
dc.date.accessioned2019-01-15T12:39:22Z
dc.date.available2019-01-15T12:39:22Z
dc.date.issued2019
dc.description© 2019 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of the European Society of Cardiology. ESC HEART FAILURE ESC Heart Failure (2019) Published online in Wiley Online Library (wileyonlinelibrary.com) DOI: 10.1002/ehf2.12399 This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.pt_PT
dc.description.abstractAIMS: Heart failure (HF) is a clinical syndrome with significant social and economic burden. We aimed to estimate the burden of HF in mainland Portugal over a 22-year time horizon, between 2014 and 2036. METHODS AND RESULTS: Heart failure burden was measured in disability-adjusted life years (DALYs), resulting from the sum of years of life lost (YLL) due to premature death and years lost due to disability (YLD). YLL were estimated based on the Portuguese mortality rates reported by the European Detailed Mortality Database. For YLD, disease duration and the overall incidence were estimated using an epidemiological model developed by the World Health Organization (DISMOD II). Disability weights were retrieved from published literature. The impact of ageing was estimated with a shift-share analysis using official demographic projections. In 2014, 4688 deaths were attributed to HF, corresponding to 4.7% of the total deaths in mainland Portugal. DALYs totalled 21 162, 53.9% due to premature death (YLL: 11 398) and 46.1% due to disability (YLD: 9765). Considering only population ageing over a 22-year horizon, the deaths and burden of HF are expected to increase by 73.0% and 27.9%, respectively, reaching 8112 deaths and 27 059 DALYs lost due to HF in 2036. DALY's growth is mainly driven by the increase of YLL, whose contribution to overall burden will increase to 62.0%. CONCLUSIONS: Heart failure is an emerging and growing health problem where significant health gains may be obtained. The projected significant increase of HF burden highlights the need to set HF as a priority for healthcare system.pt_PT
dc.description.sponsorshipThis study was supported by Novartis Farma, Produtos Farmacêuticos SA through an unrestricted grant to the Research and Development Association of Lisbon University School of Medicine (AIDFM). Funding was independent of the study outcomes. The promoter did not participate in any phase of the study.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationESC Heart Fail. 2019 Jan 8. doi: 10.1002/ehf2.12399.pt_PT
dc.identifier.doi10.1002/ehf2.12399pt_PT
dc.identifier.issn2055-5822
dc.identifier.urihttp://hdl.handle.net/10451/36408
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherWiley Open Accesspt_PT
dc.relation.publisherversionhttps://onlinelibrary.wiley.com/journal/20555822pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectHeart failurept_PT
dc.subjectGlobal burden of diseasept_PT
dc.subjectMorbiditypt_PT
dc.subjectMortalitypt_PT
dc.subjectPrematurept_PT
dc.subjectForecastingpt_PT
dc.titleThe current and future burden of heart failure in Portugalpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleESC Heart Failurept_PT
person.familyNameAscenção
person.familyNameFiorentino
person.familyNameCosta
person.familyNameCaldeira
person.familyNameBroeiro-Gonçalves
person.familyNameBorges
person.givenNameRaquel
person.givenNameFrancesca
person.givenNameJoão
person.givenNameDaniel
person.givenNamePaula
person.givenNameMargarida
person.identifier480560
person.identifier.ciencia-idDF15-F706-709E
person.identifier.ciencia-idAA19-EC35-8D01
person.identifier.ciencia-idCA13-F670-42A6
person.identifier.orcid0000-0002-9086-0973
person.identifier.orcid0000-0003-2092-3593
person.identifier.orcid0000-0002-5831-4921
person.identifier.orcid0000-0002-2520-5673
person.identifier.orcid0000-0002-5013-6171
person.identifier.orcid0000-0002-8563-6846
person.identifier.ridJ-9174-2017
person.identifier.scopus-author-id55499748300
person.identifier.scopus-author-id36623384200
person.identifier.scopus-author-id7102828573
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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