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Mortes relacionadas com cocaína : investigação médico-legal
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A cocaína é uma droga de abuso que produz efeitos agudos e crónicos, multissistémicos, com complexos e variados mecanismos de acção.
O aumento global do seu consumo tem-se repercutido num aumento da mortalidade, mortes essas, frequentemente, inesperadas e de causa ignorada, determinando a necessidade de respectiva investigação médico-legal.
Estabelecer a causa de morte e a sua possível relação com o consumo agudo e/ou crónico de cocaína, pode ser um desafio. Tal resulta, por exemplo, da dificuldade na interpretação da dose-efeito da cocaína, das associações e dos adulterantes utilizados, e dos possíveis diagnósticos diferenciais a ter em conta.
Este trabalho teve como objectivo proceder a uma revisão bibliográfica da investigação médico-legal das mortes relacionadas com a cocaína, incidindo nos mecanismos de acção desta droga, nas causas de morte com esta relacionadas, e nos respectivos resultados da autópsia médico-legal.
Cocaine is a drug of abuse that produces acute and chronic multisystemic effects, with complex and varied mechanisms of action. The overall increase in its consumption has been reflected in an increasing number of deaths many of which are often unexpected and of unknown cause, requiring medical-legal investigation. Establishing the cause of death and its possible relationship with acute and/or chronic cocaine use can be a challenge. This arises, for example, from the difficulty in interpreting the dose-effect of cocaine, the associations and adulterants used and all possible differential diagnoses to be considered. The aim of the present work was to carry out a literature review of the medical-legal investigation of cocaine-related deaths, focusing on the mechanisms of action of this drug, the causes of death related to it and the respective results of the medical-legal autopsy.
Cocaine is a drug of abuse that produces acute and chronic multisystemic effects, with complex and varied mechanisms of action. The overall increase in its consumption has been reflected in an increasing number of deaths many of which are often unexpected and of unknown cause, requiring medical-legal investigation. Establishing the cause of death and its possible relationship with acute and/or chronic cocaine use can be a challenge. This arises, for example, from the difficulty in interpreting the dose-effect of cocaine, the associations and adulterants used and all possible differential diagnoses to be considered. The aim of the present work was to carry out a literature review of the medical-legal investigation of cocaine-related deaths, focusing on the mechanisms of action of this drug, the causes of death related to it and the respective results of the medical-legal autopsy.
Descrição
Trabalho Final do Curso de Mestrado Integrado em Medicina, Faculdade de Medicina, Universidade de Lisboa, 2020
Palavras-chave
Morte relacionada com a cocaína Cardiotoxicidade da cocaína Autópsia forense Toxicologia forense Toxicidade da cocaína