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A Portuguese expert panel position paper on the management of heart failure with preserved ejection fraction: part I: pathophysiology, diagnosis and treatment

2025Journal article Open access
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dc.contributor.authorSilva-Cardoso, José
dc.contributor.authorMoreira, Emília
dc.contributor.authorTavares de Melo, Rachel
dc.contributor.authorMoraes-Sarmento, Pedro
dc.contributor.authorCardim, Nuno
dc.contributor.authorOliveira, Mario
dc.contributor.authorGavina, Cristina
dc.contributor.authorMoura, Brenda
dc.contributor.authorAraújo, Inês
dc.contributor.authorSantos, Paulo
dc.contributor.authorPeres, Marisa
dc.contributor.authorFonseca, Cândida
dc.contributor.authorFerreira, João Pedro
dc.contributor.authorMarques, Irene
dc.contributor.authorAndrade, Aurora
dc.contributor.authorBaptista, Rui
dc.contributor.authorBrito, Dulce
dc.contributor.authorCernadas, Rui
dc.contributor.authordos Santos, Jonathan
dc.contributor.authorLeite-Moreira, Adelino
dc.contributor.authorGonçalves, Lino
dc.contributor.authorFerreira, Jorge
dc.contributor.authorAguiar, Carlos
dc.contributor.authorFonseca, Manuela
dc.contributor.authorFontes-Carvalho, Ricardo
dc.contributor.authorFranco, Fátima
dc.contributor.authorLourenço, Carolina
dc.contributor.authorMartins, Elisabete
dc.contributor.authorPereira, Hélder
dc.contributor.authorSantos, Mário
dc.contributor.authorPimenta, Joana
dc.date.accessioned2025-04-11T11:13:21Z
dc.date.available2025-04-11T11:13:21Z
dc.date.issued2025
dc.description© 2025 Published by Elsevier España, S.L.U. on behalf of Sociedade Portuguesa de Cardiologia. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).pt_PT
dc.description.abstractHeart failure (HF) with preserved ejection fraction (HFpEF) affects more than 50% of HF patients worldwide, and more than 70% of HF patients aged over 65. This is a complex syndrome with a clinically heterogeneous presentation and a multifactorial pathophysiology, both of which make its diagnosis and treatment challenging. A Portuguese HF expert panel convened to address HFpEF pathophysiology and therapy, as well as appropriate management within the Portuguese context. This initiative resulted in two position papers that examine the most recently published literature in the field. The present Part I includes a review of the HFpEF literature covering pathophysiology, clinical presentation, diagnosis and treatment, including pharmacological and non-pharmacological strategies. Part II, the second paper, addresses the development of a holistic and integrated HFPEF clinical care system within the Portuguese context that is capable of reducing morbidity and mortality and improving patients' functional capacity and quality of life.pt_PT
dc.description.abstractA insuficiência cardíaca com fração de ejeção preservada (ICFEp) afeta mais de 50% dos doentes com IC em todo o mundo e mais de 70% dos doentes com IC com mais de 65 anos. É uma síndrome complexa, com uma apresentação clinicamente heterógena, e com uma fisiopatologia multifatorial, o que torna o seu diagnóstico e tratamento desafiantes. Um painel de peritos portugueses em IC reuniu-se para abordar fisiopatologia e terapêutica da ICFEp, bem como a sua gestão adequada no contexto português. Este trabalho resultou em dois artigos de posicionamento, considerando a literatura da área publicada mais recentemente. A presente Parte I inclui uma revisão da literatura sobre ICFEp abrangendo a fisiopatologia, apresentação clínica, diagnóstico e tratamento, incluindo estratégias farmacológicas e não farmacológicas. A Parte II, num segundo artigo, integra o desenvolvimento de um sistema de cuidados clínicos de ICFEp holístico e integrado no contexto português, capaz de reduzir a morbi-mortalidade e melhorar a capacidade funcional e a qualidade de vida dos doentes.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationRevista Portuguesa de Cardiologia 44 (2025) 233-243pt_PT
dc.identifier.doi10.1016/j.repc.2024.11.011pt_PT
dc.identifier.eissn2174-2030
dc.identifier.issn0870-2551
dc.identifier.urihttp://hdl.handle.net/10400.5/100150
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relation.publisherversionhttps://www.sciencedirect.com/journal/revista-portuguesa-de-cardiologiapt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectHeart failurept_PT
dc.subjectHeart failure with preserved ejection fractionpt_PT
dc.subjectHFpEFpt_PT
dc.subjectPathophysiologypt_PT
dc.subjectDiagnosispt_PT
dc.subjectTreatmentpt_PT
dc.titleA Portuguese expert panel position paper on the management of heart failure with preserved ejection fraction: part I: pathophysiology, diagnosis and treatmentpt_PT
dc.title.alternativeArtigo de posicionamento de peritos portugueses sobre a gestão da ICFEp: parte I: fisiopatologia, Diagnóstico e Tratamentopt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage243pt_PT
oaire.citation.issue4pt_PT
oaire.citation.startPage233pt_PT
oaire.citation.titleRevista Portuguesa de Cardiologiapt_PT
oaire.citation.volume44pt_PT
person.familyNameMartins Oliveira
person.familyNameBrito
person.givenNameMario Joao
person.givenNameDulce
person.identifier.ciencia-id2312-2190-19B2
person.identifier.ciencia-idF216-586F-1762
person.identifier.orcid0000-0002-8371-8354
person.identifier.orcid0000-0003-1278-1847
person.identifier.ridG-9650-2016
person.identifier.scopus-author-id7004510538
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication81e0b444-8832-47a8-a911-2f89eb33545d
relation.isAuthorOfPublication196a2934-1434-433c-9735-81acb6fbe587
relation.isAuthorOfPublication.latestForDiscovery196a2934-1434-433c-9735-81acb6fbe587

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