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Cervical lymph node schwannoma : an unexpected diagnosis

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dc.contributor.authorSilvestre, Catarina Falcão
dc.contributor.authorAlmeida-Tavares, Joana
dc.contributor.authorLópez-Presa, Dolores
dc.contributor.authorSantos, Vanessa Rebelo dos
dc.contributor.authorRocha, José
dc.contributor.authorBugalho, Maria João
dc.date.accessioned2021-07-19T13:20:46Z
dc.date.available2021-07-19T13:20:46Z
dc.date.issued2019
dc.description© The Author(s) 2019. Sage. This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).pt_PT
dc.description.abstractIntroduction: Schwannomas-Schwann cells-originating tumors-may develop in many locations. However, primary schwannomas arising within lymph nodes are extremely rare, with only a few cases described to this date in the English literature. For the intranodal location, most of the cases are described in the abdominal cavity. In these cases, clinicians may consider and check for familial disorders, such as neurofibromatosis type 2 (NF2) and schwannomatosis also called neurofibromatosis type 3. Schwannomas are benign neoplasms. Histologically, differential diagnosis for spindle-cell lesions in lymph nodes is important and must be done carefully, mainly because they may be attributable to metastatic disease. We report a case of a primary schwannoma arising in a cervical lymph node. Background: Primary schwannomas arising within lymph nodes are extremely rare, with only a few cases reported. Since they are benign neoplasms, the differential diagnosis with other intranodal spindle cell lesions, mostly malignant, is important. Methods: An asymptomatic 69-year-old woman, previously submitted to left hemithyroidectomy for a benign folicular nodule, underwent thyroidectomy totalization following the identification of a large thyroid nodule in routine evaluation. Results: Gross and microscopic examination and ancillary studies were consistent with the diagnosis of intranodal schwannoma. The patient had acquired bilateral hypoacusia. Therefore, type 2 neurofibromatosis was considered and vestibular schwannomas ruled out. Conclusion: Herein, we present the second case of a primary schwannoma in a cervical lymph node reported so far. The relevance of the differential diagnosis is highlighted.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationClin Pathol. 2019 Feb 27;12pt_PT
dc.identifier.doi10.1177/2632010X19829239pt_PT
dc.identifier.eissn2632-010X
dc.identifier.urihttp://hdl.handle.net/10451/48998
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherSAGE Publishingpt_PT
dc.relation.publisherversionhttps://journals.sagepub.com/home/patpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/pt_PT
dc.subjectSchwannomapt_PT
dc.subjectIntranodalpt_PT
dc.subjectLymph nodept_PT
dc.subjectNeurilemmomapt_PT
dc.subjectSpindle cellspt_PT
dc.titleCervical lymph node schwannoma : an unexpected diagnosispt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleClinical Pathologypt_PT
oaire.citation.volume12pt_PT
person.familyNameAlmeida-Tavares
person.familyNameBugalho
person.givenNameJoana
person.givenNameMaria João
person.identifier1596200
person.identifier.ciencia-id7016-E6DD-F3F5
person.identifier.ciencia-idD51C-30D5-71FC
person.identifier.orcid0000-0001-6273-7735
person.identifier.orcid0000-0003-0357-7350
person.identifier.scopus-author-id35582359500
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationfff9f1f5-674a-489c-89cc-fca29862d10e
relation.isAuthorOfPublicationbe8c1585-6357-4383-9c99-27c8169ff4cf
relation.isAuthorOfPublication.latestForDiscoverybe8c1585-6357-4383-9c99-27c8169ff4cf

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