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The population genomics of archaeological transition in west Iberia: Investigation of ancient substructure using imputation and haplotype-based methods

2017Journal article Open access
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dc.contributor.authorMartiniano, Rui
dc.contributor.authorCassidy, Lara M.
dc.contributor.authorÓ'Maoldúin, Ros
dc.contributor.authorMcLaughlin, Russell
dc.contributor.authorSilva, Nuno M.
dc.contributor.authorManco, Licinio
dc.contributor.authorFidalgo, Daniel
dc.contributor.authorPereira, Tania
dc.contributor.authorCoelho, Maria J.
dc.contributor.authorSerra, Miguel
dc.contributor.authorBurger, Joachim
dc.contributor.authorParreira, Rui
dc.contributor.authorMoran, Elena
dc.contributor.authorValera, Antonio C.
dc.contributor.authorPorfirio, Eduardo
dc.contributor.authorBoaventura, Rui
dc.contributor.authorSilva, Ana M.
dc.contributor.authorBradley, Daniel G.
dc.date.accessioned2018-01-29T13:07:58Z
dc.date.available2018-01-29T13:07:58Z
dc.date.issued2017
dc.description.abstractWe analyse new genomic data (0.05-2.95x) from 14 ancient individuals from Portugal distributed from the Middle Neolithic (4200-3500 BC) to the Middle Bronze Age (1740-1430 BC) and impute genomewide diploid genotypes in these together with published ancient Eurasians. While discontinuity is evident in the transition to agriculture across the region, sensitive haplotype-based analyses suggest a significant degree of local hunter-gatherer contribution to later Iberian Neolithic populations. A more subtle genetic influx is also apparent in the Bronze Age, detectable from analyses including haplotype sharing with both ancient and modern genomes, D-statistics and Y-chromosome lineages. However, the limited nature of this introgression contrasts with the major Steppe migration turnovers within third Millennium northern Europe and echoes the survival of non-Indo-European language in Iberia. Changes in genomic estimates of individual height across Europe are also associated with these major cultural transitions, and ancestral components continue to correlate with modern differences in stature.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationCitation: Martiniano R, Cassidy LM, O´’Maoldu´in R, McLaughlin R, Silva NM, Manco L, et al. (2017) The population genomics of archaeological transition in west Iberia: Investigation of ancient substructure using imputation and haplotypebased methods. PLoS Genet 13(7): e1006852. https://doi.org/10.1371/journal.pgen.1006852pt_PT
dc.identifier.doi10.1371/journal.pgen.1006852pt_PT
dc.identifier.issn1553-7404
dc.identifier.issn1553-7390
dc.identifier.urihttp://hdl.handle.net/10451/31169
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.relation.publisherversionhttp://www.ncbi.nlm.nih.gov/pubmed/28749934pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectArchaeologypt_PT
dc.subjectChromosomes, Human, Ypt_PT
dc.subjectDatabases, Geneticpt_PT
dc.subjectEuropept_PT
dc.subjectFemalept_PT
dc.subjectGenetic variationpt_PT
dc.subjectPopulation geneticspt_PT
dc.subjectHuman genomept_PT
dc.subjectGenomicspt_PT
dc.subjectGenotypept_PT
dc.subjectHumanspt_PT
dc.subjectMalept_PT
dc.subjectPortugalpt_PT
dc.subjectSequence Analysis, DNApt_PT
dc.subjectHaplotypespt_PT
dc.titleThe population genomics of archaeological transition in west Iberia: Investigation of ancient substructure using imputation and haplotype-based methodspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titlePLoS Geneticspt_PT
oaire.citation.volume13.7pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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