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An overview of systematic reviews of economic evaluations of pharmacy-based public health interventions : addressing methodological challenges

dc.contributor.authorCosta, Suzete
dc.contributor.authorCary, Maria
dc.contributor.authorHelling, Dennis K.
dc.contributor.authorPereira, João
dc.contributor.authorMateus, Céu
dc.date.accessioned2020-04-01T10:37:22Z
dc.date.available2020-04-01T10:37:22Z
dc.date.issued2019
dc.description.abstractBackground: Pharmacy interventions are a subset of public health interventions and its research is usually performed within the scope of a trial. The economic evaluation of pharmacy interventions requires certain considerations which have some similarities to those of public health interventions and to economic evaluations alongside trials. The objective of this research is to perform an overview of systematic reviews of economic evaluations of pharmacy services and triangulate results with recommendations for economic evaluations of both public health interventions and alongside trials. Methods:(1) Exploratory review of recommendations on the economic evaluation of public health interventions, (2)exploratory review of recommendations for conducting economic evaluations alongside trials, (3) overview of systematic reviews of economic evaluations of pharmacy interventions (protocol registered with PROSPERO 2016 outlining information sources, inclusion criteria, appraisal of reviews and synthesis methods). Results: Fourteen systematic reviews containing 75 index publications were included. Reviews reported favourable economic findings for 71% of studies with full economic evaluations. The types of economic analysis are diverse. Two critical quality domains are absent from most reviews. Key findings include the following: certain types of risk of bias, wider scope of study designs, and most economic quality criteria met but some issues unresolved or unclear. Triangulation revealed additional gaps. Limitations include choice of critical quality domains and potential biases in the overview process. Conclusions: Economic evaluations of pharmacy-based public health interventions seem to follow most economic quality criteria, but there are still some issues in certain key areas to improve. These findings may assist in improving the design of pilot trials of economic evaluations in pharmacy, leading to robust evidence for payers. Based on the findings, we propose a methodological approach for the economic evaluation of pharmacy-based public health interventions. Systematic review registration: PROSPERO CRD42016032768pt_PT
dc.description.sponsorship© The Author(s). 2019 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver(http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationSystematic Reviews, Volume 8, Article number: 272 (2019)pt_PT
dc.identifier.doi10.1186/s13643-019-1177-3pt_PT
dc.identifier.issn2046-4053
dc.identifier.urihttp://hdl.handle.net/10451/42654
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherBMCpt_PT
dc.relation.publisherversionhttps://systematicreviewsjournal.biomedcentral.com/pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectOverviewpt_PT
dc.subjectUmbrella review,pt_PT
dc.subjectSystematic reviewpt_PT
dc.subjectEconomic evaluationpt_PT
dc.subjectCost-effectivenesspt_PT
dc.subjectCommunity pharmacypt_PT
dc.subjectPharmacy interventionspt_PT
dc.subjectPharmacy servicespt_PT
dc.subjectPublic health interventionspt_PT
dc.subjectMethodspt_PT
dc.titleAn overview of systematic reviews of economic evaluations of pharmacy-based public health interventions : addressing methodological challengespt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue1pt_PT
oaire.citation.startPage272pt_PT
oaire.citation.titleSystematic Reviewspt_PT
oaire.citation.volume8pt_PT
person.familyNameCosta
person.givenNameSuzete
person.identifier.orcid0000-0002-4521-5473
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication44ded07d-217a-4c1d-bd60-934fa4097aac
relation.isAuthorOfPublication.latestForDiscovery44ded07d-217a-4c1d-bd60-934fa4097aac

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