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Sutureless bioprosthesis for aortic valve replacement: surgical and clinical outcomes

dc.contributor.authorFerreira, Ricardo
dc.contributor.authorRua, Nuno
dc.contributor.authorSena, André
dc.contributor.authorVelho, Tiago R.
dc.contributor.authorGoncalves, Joao
dc.contributor.authorJunqueira, Nádia
dc.contributor.authorAlmeida, Ana G.
dc.contributor.authorNobre, Angelo
dc.contributor.authorPinto, Fausto J.
dc.date.accessioned2022-11-22T12:53:20Z
dc.date.available2022-11-22T12:53:20Z
dc.date.issued2022
dc.description© 2022 The Authors. Journal of Cardiac Surgery published by Wiley Periodicals LLC. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.pt_PT
dc.description.abstractBackground: Aortic valve stenosis is the most common adult valve disease in industrialized countries. The aging population and the increase in comorbidities urge the development of safer alternatives to the current surgical treatment. Sutureless bioprosthesis has shown promising results, especially in complex procedures and in patients requiring concomitant surgeries. Objectives: Assess the clinical and hemodynamic performance, safety, and durability of the Perceval® prosthetic valve. Methods: This single-center retrospective longitudinal cohort study collected data from all adult patients with aortic valve disease who underwent aortic valve replacement with a Perceval® prosthetic valve between February 2015 and October 2020. Of the 196 patients included (mean age 77.20 ± 5.08 years; 45.4% female; mean EuroSCORE II 2.91 ± 2.20%), the majority had aortic stenosis. Results: Overall mean cross-clamp and cardiopulmonary bypass times were 33.31 ± 14.09 min and 45.55 ± 19.04 min, respectively. Mean intensive care unit and hospital stay were 3.32 ± 3.24 days and 7.70 ± 5.82 days, respectively. Procedural success was 98.99%, as two explants occurred. Four valves were reimplanted due to intraoperative misplacement. Mean transvalvular gradients were 7.82 ± 3.62 mmHg. Pacemaker implantation occurred in 12.8% of patients, new-onset atrial fibrillation in 21.9% and renal replacement support was necessary for 3.1%. Early mortality was 2.0%. We report no structural valve deterioration, strokes, or endocarditis, and one successfully treated valve thrombosis. Conclusions: Our study confirms the excellent clinical and hemodynamic performance and safety of a truly sutureless aortic valve, up to a 5-year follow-up. These results were consistent in isolated and concomitant interventions, solidifying this device as a viable option for the treatment of isolated aortic valve disease.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationJ Card Surg. 2022;1–9pt_PT
dc.identifier.doi10.1111/jocs.17113pt_PT
dc.identifier.eissn1540-8191
dc.identifier.issn0886-0440
dc.identifier.urihttp://hdl.handle.net/10451/55201
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherWileypt_PT
dc.relation.publisherversionhttps://onlinelibrary.wiley.com/journal/15408191pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectPerceval® valvept_PT
dc.subjectAortic valve diseasept_PT
dc.subjectAortic valve replacementpt_PT
dc.subjectAortic valve stenosispt_PT
dc.subjectSutureless bioprosthesispt_PT
dc.titleSutureless bioprosthesis for aortic valve replacement: surgical and clinical outcomespt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleJournal of Cardiac Surgerypt_PT
person.familyNameFerreira
person.familyNameSena
person.familyNameVelho
person.familyNameGoncalves
person.familyNameAlmeida
person.familyNameLucas Pereira Nobre
person.familyNamePinto
person.givenNameRicardo
person.givenNameAndré
person.givenNameTiago
person.givenNameJoao
person.givenNameAna Gomes de
person.givenNameAngelo Manuel
person.givenNameFausto J.
person.identifier1308889
person.identifier.ciencia-id9C14-C345-564F
person.identifier.ciencia-id4717-323E-A9BB
person.identifier.ciencia-idB11B-9815-C46F
person.identifier.ciencia-id3610-3184-3042
person.identifier.ciencia-id6D1C-B056-A429
person.identifier.ciencia-idC311-AEDD-6DBB
person.identifier.orcid0000-0003-0084-3916
person.identifier.orcid0000-0003-2278-7505
person.identifier.orcid0000-0002-0455-8189
person.identifier.orcid0000-0002-1245-3715
person.identifier.orcid0000-0003-0360-4363
person.identifier.orcid0000-0002-8034-4529
person.identifier.ridB-2013-2008
person.identifier.ridG-9363-2015
person.identifier.scopus-author-id7103326175
person.identifier.scopus-author-id55628683100
person.identifier.scopus-author-id7102740158
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication65776796-bd8b-4fca-9bb1-f124748a8859
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relation.isAuthorOfPublication.latestForDiscovery91eeef2a-10a1-434a-afb3-f9675f05fede

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