Stereo-EEG recording and minimally invasive treatment of a periventricular nodular heterotopy : two-in-one strategy

Franco, Ana Catarina; Peralta, Ana Rita; Morgado, Carlos; Gonçalves Ferreira, António; Rainha Campos, Alexandre; Bentes, Carla

http://hdl.handle.net/10451/46094

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Authors

Franco, Ana Catarina

Peralta, Ana Rita

Morgado, Carlos

Gonçalves Ferreira, António

Rainha Campos, Alexandre

Bentes, Carla

Abstract(s)

Periventricular nodular heterotopias (PNHs) are malformations of cortical development. These are frequently associated with drug-resistant epilepsy. Stereo-electroencephalography (SEEG) is usually part of the epilepsy pre-surgical evaluation in order to find the epileptogenic zone (EZ). SEEG-guided radiofrequency-thermocoagulation (RF-TC) has been used to ablate or disrupt the EZ and proved to be effective, with seizure freedom rates of 38-50%, a responder rate of 81% and a favorable safety profile.