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Incidence of acute aortic dissections in patients with out of hospital cardiac arrest: a systematic review and meta-analysis of observational studies

2022Journal article Open access
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dc.contributor.authorMelo, Ryan
dc.contributor.authorMachado, Carolina
dc.contributor.authorCaldeira, Daniel
dc.contributor.authorAlves, Mariana
dc.contributor.authorLopes, Alice
dc.contributor.authorSerrano, Maria
dc.contributor.authorFernandes E Fernandes, Ruy
dc.contributor.authorPedro, Luís M
dc.date.accessioned2022-01-12T15:08:07Z
dc.date.available2022-01-12T15:08:07Z
dc.date.issued2022
dc.description© 2021 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.description.abstractObjectives: Acute Aortic dissection (AAD) may present as out-of-hospital cardiac arrest (OHCA). However, the incidence of this presentation is not well known. Our aim was to perform a systematic review and meta-analysis of all observational studies reporting on the incidence of AAD in patients with OHCA. Methods: We searched MEDLINE, CENTRAL, PsycInfo, Web of Science Core Collection and OpenGrey databases from inception to March-2021, for observational studies reporting on the incidence of AAD in patients with OHCA. Data was pooled using a random-effects model of proportions. The primary outcome was the incidence of AAD in OHCA patients. Secondary outcomes were the incidence of type A aortic dissections (TAAD) and type B aortic dissections (TBAD) in OHCA patients, overall mortality following AAD-OHCA and risk of death in AAD-OHCA patients compared to risk of death of non-AAD-OHCA patients. Results: Fourteen studies were included. The pooled calculated incidence of OHCA due to AAD was 4.39% (95 %CI: 2.55; 6.8). Incidence of OHCA due to TAAD was 7.18% (95 %CI: 5.61; 8.93) and incidence of OHCA due to TBAD was 0.47% (95 %CI: 0.18; 0.85). Overall mortality following OHCA due to AAD was 100% (95 %CI: 97.62; 100). The risk of death in AAD-OHCA patients compared with non-AAD-OHCA patients was 1.10 (95 %CI: 0.94; 1.30). Conclusion: AAD as a cause of OHCA is more frequent than previously thought. Prognosis is dire, as it is invariably lethal. These findings should lead to a higher awareness of AAD when approaching a patient with OHCA and to future studies on this matter.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationInt J Cardiol Heart Vasc. 2021 Dec 23;38:100934pt_PT
dc.identifier.doi10.1016/j.ijcha.2021.100934pt_PT
dc.identifier.issn2352-9067
dc.identifier.urihttp://hdl.handle.net/10451/50786
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relation.publisherversionhttps://www.sciencedirect.com/journal/ijc-heart-and-vasculaturept_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectAortic dissectionpt_PT
dc.subjectIncidencept_PT
dc.subjectMeta-analysispt_PT
dc.subjectOut-of-hospital cardiac arrestpt_PT
dc.subjectSystematic reviewpt_PT
dc.titleIncidence of acute aortic dissections in patients with out of hospital cardiac arrest: a systematic review and meta-analysis of observational studiespt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleIJC Heart & Vasculaturept_PT
person.familyNameGouveia e Melo
person.familyNameCaldeira
person.familyNameAlves
person.familyNameLopes
person.familyNameFernandes e Fernandes
person.familyNamePedro
person.givenNameRyan
person.givenNameDaniel
person.givenNameMariana
person.givenNameAlice
person.givenNameRuy
person.givenNameLuís
person.identifier1153684
person.identifier.ciencia-id211B-B548-CE4E
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person.identifier.ciencia-id0718-09A9-D4EA
person.identifier.ciencia-id8D12-0BD7-11B5
person.identifier.ciencia-idB710-641D-77AD
person.identifier.ciencia-id0B14-1812-24DC
person.identifier.orcid0000-0001-8327-6384
person.identifier.orcid0000-0002-2520-5673
person.identifier.orcid0000-0002-1369-8423
person.identifier.orcid0000-0002-1957-7614
person.identifier.orcid0000-0003-1619-8851
person.identifier.orcid0000-0003-4310-9324
person.identifier.ridO-3034-2016
person.identifier.scopus-author-id36623384200
person.identifier.scopus-author-id56591535500
person.identifier.scopus-author-id57203041538
person.identifier.scopus-author-id39761284300
person.identifier.scopus-author-id7004454630
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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