Publicação
Subsyndromal delirium in critically ill patients: cognitive and functional long-term outcomes
| dc.contributor.author | Paulino, Maria Carolina | |
| dc.contributor.author | Conceição, Catarina | |
| dc.contributor.author | Silvestre, Joana | |
| dc.contributor.author | Lopes, Maria Inês | |
| dc.contributor.author | Gonçalves, Hernâni | |
| dc.contributor.author | Dias, Cláudia Camila | |
| dc.contributor.author | Serafim, Rodrigo | |
| dc.contributor.author | Salluh, Jorge I. F. | |
| dc.contributor.author | Póvoa, Pedro | |
| dc.date.accessioned | 2023-11-09T14:38:43Z | |
| dc.date.available | 2023-11-09T14:38:43Z | |
| dc.date.issued | 2023 | |
| dc.description | © 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). | pt_PT |
| dc.description.abstract | Subsyndromal delirium (SSD) in the Intensive Care Unit (ICU) is associated with an increased morbidity with unknown post-discharge functional and cognitive outcomes. We performed a prospective multicenter study to analyze the mental status of patients during their first 72 h after ICU admission and its trajectory, with follow-ups at 3 and 6 months after hospital discharge. Amongst the 106 included patients, SSD occurred in 24.5% (n = 26) and was associated with the duration of mechanical ventilation (p = 0.003) and the length of the ICU stay (p = 0.002). After the initial 72 h, most of the SSD patients (30.8%) improved and no longer had SSD; 19.2% continued to experience SSD and one patient (3.8%) progressed to delirium. The post-hospital discharge survival rate for the SSD patients was 100% at 3 months and 87.5% at 6 months. At admission, 96.2% of the SSD patients were fully independent in daily living activities, 66.7% at 3-month follow-up, and 100% at 6-month follow-up. Most SSD patients demonstrated a cognitive decline from admission to 3-month follow-up and improved at 6 months (IQCODE-SF: admission 3.13, p < 0.001; 3 months 3.41, p = 0.019; 6 months 3.19, p = 0.194). We concluded that early SSD is associated with worse outcomes, mainly a transitory cognitive decline after hospital discharge at 3 months, with an improvement at 6 months. This highlights the need to prevent and identify this condition during ICU stays. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.citation | J Clin Med. 2023 Oct 4;12(19):6363 | pt_PT |
| dc.identifier.doi | 10.3390/jcm12196363 | pt_PT |
| dc.identifier.eissn | 2077-0383 | |
| dc.identifier.uri | http://hdl.handle.net/10451/60253 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | MDPI | pt_PT |
| dc.relation.publisherversion | https://www.mdpi.com/journal/jcm | pt_PT |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | pt_PT |
| dc.subject | ICU | pt_PT |
| dc.subject | Cognitive dysfunction | pt_PT |
| dc.subject | Delirium | pt_PT |
| dc.subject | Long-term outcome | pt_PT |
| dc.subject | Subsyndromal delirium | pt_PT |
| dc.title | Subsyndromal delirium in critically ill patients: cognitive and functional long-term outcomes | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.issue | 19 | pt_PT |
| oaire.citation.title | Journal of Clinical Medicine | pt_PT |
| oaire.citation.volume | 12 | pt_PT |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | article | pt_PT |