dc.contributor.advisor	Sardinha, Luis Fernando Cordeiro Bettencourt
dc.contributor.author	Rocha, Paulo Manuel Espadinha Pinheiro da
dc.date.accessioned	2008-12-29T11:46:41Z
dc.date.available	2008-12-29T11:46:41Z
dc.date.issued	2007-02-16
dc.description	Tese de Doutoramento em Motricidade Humana na especialidade de Saúde e Condição Física	en
dc.description.abstract	This thesis sought to analyze the relationships between body composition markers and metabolic syndrome features in overweight and obese women, being structured in three scientific problems. The first scientific problem investigated the separate contributions of waist and hip circumference to proinflammatory and atherothrombotic metabolic syndrome disturbances. Associations of thigh adipose and muscle tissue compartments with metabolic features were also studied. For a given waist circumference, a larger hip circumference predicted a lower diabetogenic and atherothrombotic risk. Femoral-gluteal adipose tissue seems to mediate this protective role. The second problem studied the independent associations of abdominal and thigh adipose tissue compartments with metabolic syndrome clinical features. Contrarily to visceral adipose tissue, a larger thigh subcutaneous adipose tissue was related with a lower thrombotic and atherogenic risk. The last problem analyzed the independent relations of abdominal and thigh adipose tissue compartments with liver fat. The associations of proinflammatory and atherothrombotic risk factors with liver fat were also studied. Thigh subfascial adipose tissue was inversely associated with liver fat, suggesting that this thigh fat depot may play a protective role against ectopic liver fat storage. An abdominal obesity phenotype associated with a diabetogenic, inflammatory, and atherothrombotic metabolic profile may to contribute to liver lipotoxicity.	en
dc.description.sponsorship	FCT	en
dc.identifier.uri	http://hdl.handle.net/10400.5/483
dc.language.iso	eng	en
dc.subject	Adipose tissue	en
dc.subject	Body composition	en
dc.subject	Cardiovascular disease	en
dc.subject	Metabolic syndrome	en
dc.subject	Obesity	en
dc.subject	Risk factors	en
dc.subject	Composição corporal	en
dc.subject	Doenças cardiovasculares	en
dc.subject	Factores de risco	en
dc.subject	Obesidade	en
dc.subject	Síndrome metabólica	en
dc.subject	Tecido adiposo	en
dc.title	Body Composition and metabolic syndrome features in overweight and obese women	en
dc.type	doctoral thesis
dspace.entity.type	Publication
rcaap.rights	openAccess	en
rcaap.type	doctoralThesis	en

Body Composition and metabolic syndrome features in overweight and obese women

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