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Non-adherence to antibiotic therapy in patients visiting community pharmacies
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Orientador(es)
Resumo(s)
Background Patient non-adherence to antibiotic therapy may lead to therapeutic failure, re-infection, and bacterial resistance. Assessing the factors associated with this problem is important for promoting rational use of antibiotics. Objective This study aimed to measure prevalence and reasons for non-adherence to antibiotic treatment and to identify associated factors. Method Patients were recruited for the study in community pharmacies in Lisbon,
Portugal, from February to April, 2009. Data from prescriptions for oral antibiotics were collected for adult
subjects. Adherence to treatment was assessed with a modified Portuguese version of the Morisky scale. Factors
associated with non-adherence were identified through bivariate analysis and logistic regression models. Results A
total of 243 patients were included in the study. They had a mean age 46.5 ± 16.6 years and 74.5 % of the sample was
female. The prevalence of non-adherence was 57.7 % and was related to delays and failures in taking the prescribed
medicine. Increasing age (OR 0.97), difficulty in buying the antibiotic (OR 2.34), duration of treatment (OR 1.28),
difficulty with ingestion (OR 3.08), and satisfaction with the information given by physician (OR 0.33) were identified
as independent factors associated with non-adherence. Conclusion Non-adherence to antibiotics is common
in the community setting. Factors related to the antibiotic, the patient, and the patient-physician relationship should be
addressed to promote adherence. Pharmacists should provide information to patients about correct use of antibiotics
and address barriers to adherence.
Descrição
Devido a uma gralha da responsabilidade da publicação IJCP, o nome do último autor encontra-se incompleto, faltando o apelido "Nicola". Aguarda-se errata vinda da editora.
Link para a versão integral / Link to full online version: http://link.springer.com/article/10.1007%2Fs11096-013-9850-4
© Koninklijke Nederlandse Maatschappij ter bevordering der Pharmacie 2013
Link para a versão integral / Link to full online version: http://link.springer.com/article/10.1007%2Fs11096-013-9850-4
© Koninklijke Nederlandse Maatschappij ter bevordering der Pharmacie 2013
Palavras-chave
Antibiotics Bacterial resistance Community pharmacies Patient adherence Portugal