Publicação
The influence of L-PRF in socket healing with immediate implants: proposal of a prospective randomized split-mouth study design
| datacite.subject.fos | Ciências Médicas::Medicina Clínica | pt_PT |
| dc.contributor.advisor | Caramês, João, 1962- | |
| dc.contributor.advisor | Francisco, Helena | |
| dc.contributor.author | Gonçalves, Natielle dos Santos | |
| dc.date.accessioned | 2018-12-04T16:00:09Z | |
| dc.date.available | 2018-12-04T16:00:09Z | |
| dc.date.issued | 2018 | |
| dc.description | Tese de mestrado, Medicina Dentária, Universidade de Lisboa, Faculdade de Medicina Dentária, 2018 | pt_PT |
| dc.description.abstract | Introduction: Tooth extractions are one of the most common procedures in dentistry, leading to important changes in the edentulous ridge. These may not allow a satisfactory positioning of dental implants and they may compromise the result of the prosthetic rehabilitation. Immediate implants can be a viable treatment option, reducing the number of surgical procedures and the treatment period. However, one potential disadvantage is the gap formed between implant and buccal bone. To regenerate this bone defect, techniques have been developed that include the placement of different grafting materials such as xenografts and most recently, Leukocytes and Platelet-rich Fibrin (L-PRF). The aim of this prospective split-mouth study is to analyze the effectiveness of L-PRF regeneration in post-extraction sockets with immediate implant placement, compared to regeneration with xenograft biomaterial (Bio Oss®). Materials and Methods: Participants who fill the inclusion criteria will be part of both groups. Control and test site will be randomly assigned, at surgery day. At the surgery day, L-PRF membrane will be prepared and the implant will be placed in post-extraction socket. The gap will be filled with L-PRF membrane in test site and xenograft in control site. Clinical evaluation includes intra-oral photographs, healing tissue evaluation and keratinized soft tissue gain. Radiographic examination will consist in periapical radiographs and CBCT to measure bone marginal loss and bony defect regeneration. Follow-up appointments will be performed at day 10 and 30, 3 months, 6 months and 1 year after surgery. Participants will fill a questionnaire to self-assess post-operative pain. Finally, 1 year after surgery, implant’s survival and success will be assessed. Main Considerations: The literature indicates good results concerning L-PRF application. However, there is a limited number of studies and a lack of standardization, thus exposing the need for further RCTs assessing the effect of L-PRF on bone and soft tissue regeneration. | pt_PT |
| dc.identifier.tid | 201988550 | pt_PT |
| dc.identifier.uri | http://hdl.handle.net/10451/35642 | |
| dc.language.iso | eng | pt_PT |
| dc.subject | Implantes dentários | pt_PT |
| dc.subject | Teses de mestrado - 2018 | pt_PT |
| dc.title | The influence of L-PRF in socket healing with immediate implants: proposal of a prospective randomized split-mouth study design | pt_PT |
| dc.type | master thesis | |
| dspace.entity.type | Publication | |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | masterThesis | pt_PT |
| thesis.degree.name | Mestrado Integrado em Medicina Dentária | pt_PT |