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XEN‐augmented Baerveldt surgical success rate and comparison with the Ahmed Valve

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dc.contributor.authorJorge Teixeira, Filipa
dc.contributor.authorSousa, David Cordeiro
dc.contributor.authorMachado, Nuno Martins
dc.contributor.authorCaiado, Filipa
dc.contributor.authorCorreia Barão, Rafael
dc.contributor.authorSens, Paula
dc.contributor.authorPinto, Luis
dc.date.accessioned2020-12-09T18:38:15Z
dc.date.available2020-12-09T18:38:15Z
dc.date.issued2020
dc.description© 2020 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.pt_PT
dc.description.abstractPurpose: The Baerveldt-XEN technique is intended to reduce the risk of early hypotony after Baerveldt implant, while keeping a good long-term intra-ocular pressure (IOP) control. The aim of this study is to discuss the surgical success rate of the Baerveldt-XEN and compare it with the commercially available flow-restrictor device (Ahmed glaucoma valve - AGV). Methods: Single-centre, cohort study. Consecutive glaucoma patients with uncontrolled IOP > 21 mmHg on maximum tolerated medical therapy, and who had an aqueous shunt as the planned surgical procedure. Patients underwent implantation of Baerveldt-XEN. An age-, gender- and glaucoma aetiology-matched database of AGV patients was used for comparison. Complete surgical success was defined as a final IOP between 6 and 21 mmHg, and 20% reduction from baseline with no need for IOP-lowering medication. Qualified success was the same criteria but resorting to medications. Results: Twenty-four eyes from 24 subjects with glaucoma were included in this study, 12 patients underwent Baerveldt-XEN implantation and 12 AGV. Twelve months after the Baerveldt-XEN implant, the IOP reduced from 33 ± 9 mmHg to 14 ± 3 mmHg (p < 0.001). The qualified and complete success rate was 50% and 25%, respectively. With the AGV, the IOP reduced from 29 ± 7 mmHg to 16 ± 7 mmHg (p = 0.001). The matched AGV group compared to the Baerveldt-XEN, presented a higher complete success rate (58.3%) and a qualified success rate of 33.3% (p = 0.72). No sight-threatening complications were recorded in both groups. Conclusions: The Baerveldt-XEN disclosed a low complete success rate at 1 year of follow-up, although with no major safety concerns. While studies with a longer follow-up are needed to demonstrate the potential advantages and disadvantages of the Baerveldt-XEN, this technique may be less likely to achieve drop-free efficacy when compared to other flow-restrictor strategies.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationActa Ophthalmol. 2020 Nov;98(7):e870-e875pt_PT
dc.identifier.doi10.1111/aos.14400pt_PT
dc.identifier.eissn1755-3768
dc.identifier.issn1755-375X
dc.identifier.urihttp://hdl.handle.net/10451/45217
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherJohn Wiley & Sons, Inc.pt_PT
dc.relation.publisherversionhttps://onlinelibrary.wiley.com/journal/17553768pt_PT
dc.subjectAhmedpt_PT
dc.subjectBaerveldtpt_PT
dc.subjectXENpt_PT
dc.subjectDevicept_PT
dc.subjectGlaucoma drainage implantpt_PT
dc.titleXEN‐augmented Baerveldt surgical success rate and comparison with the Ahmed Valvept_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPagee875pt_PT
oaire.citation.issue7pt_PT
oaire.citation.startPagee870pt_PT
oaire.citation.titleActa Ophthalmologicapt_PT
oaire.citation.volume98pt_PT
person.familyNameJorge Teixeira
person.familyNameSousa
person.familyNameCaiado
person.familyNameCorreia Barão
person.familyNameAbegão Pinto
person.givenNameFilipa
person.givenNameDavid Cordeiro
person.givenNameFilipa
person.givenNameRafael
person.givenNameLuis
person.identifier707480
person.identifier.ciencia-idDF1D-9635-8FC4
person.identifier.ciencia-idF216-4AFA-8E65
person.identifier.orcid0000-0003-2884-8436
person.identifier.orcid0000-0002-7680-0325
person.identifier.orcid0000-0002-3063-7753
person.identifier.orcid0000-0002-3102-1969
person.identifier.orcid0000-0002-9960-7579
person.identifier.ridA-6192-2015
person.identifier.scopus-author-id57188627862
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT
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relation.isAuthorOfPublication.latestForDiscovery3ef7542a-3f88-4310-81be-9aaf3751489f

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