Publication
Effects of the administration of a bolus of 7,2% hypertonic saline solution in horses with colic, as a part of medical treatment : a preliminary study
| dc.contributor.advisor | Buchanan, Benjamin Rice | |
| dc.contributor.advisor | Tilley, Paula Alexandra Botelho Garcia de Andrade Pimenta | |
| dc.contributor.author | Stilwell, Catarina Campos de Carvalho | |
| dc.date.accessioned | 2017-09-14T12:46:54Z | |
| dc.date.available | 2017-09-14T12:46:54Z | |
| dc.date.issued | 2017-01-20 | |
| dc.description | Dissertação de Mestrado Integrado em Medicina Veterinária | pt_PT |
| dc.description.abstract | The present study is a preliminary study that aims to determine the existence of a beneficial effect in the administration of a bolus of 7,2% hypertonic saline solution, as a part of medical treatment, to horses suffering from gastrointestinal colic and in need of IV fluid therapy. Eight horses were enrolled in this study and divided into two groups: LRS group that received a 2L bolus of lactated Ringer’s solution and HSS group that received a 2L bolus of 7,2% hypertonic saline solution. Blood pressures and several blood parameters were collected for all horses before (T0), immediately after (T1) and 90 minutes after (T2) the administration of the fluid bolus. Between T1 and T2 all horses received approximately 10 litters of plasma - Lyte A, intravenously. No horse received oral fluids for the duration of this study. Blood pressures increased at T1 for the HSS group while all blood parameters decreased, except for blood urea nitrogen which remained similar to T0. At T2, the blood pressures for the HSS group were lower than at T1 but higher than at T0. Lactate concentrations decreased continuously for the HSS group and increased at T1 for the LRS group. Despite the small sample of horses used in this study, there seems to exist strong evidence of the beneficial effects of the administration of hypertonic saline solution to horses with medical colics. | en_ENG |
| dc.description.abstract | RESUMO - Efeitos da administração de um bólus de soro salino hipertónico a 7,2% em cavalos com colica, como parte do tratamento médico: um estudo preliminar - O presente estudo tem como objectivo determinar a existência de um efeito benéfico na administração de um bólus de soro salino hipertónico a 7,2%, como parte do tratamento médico, a cavalos com cólica gastrointestinal e com necessidade de receber fluidoterapia IV. Foram admitidos oito cavalos neste estudo e divididos em dois grupos: grupo LRS que recebeu um bólus de 2L de lactato de Ringer e o grupo HSS que recebeu um bólus de 2L de soro salino hipertónico a 7,2%. Pressões sanguíneas e vários parâmetros sanguíneos foram avaliados em todos os cavalos antes (T0), imendiatamente depois (T1) e 90 minutos depois (T2) da administração do bólus de fluido. Entre T1 e T2 todos os cavalos receberam cerca de 10 litros de plasma - Lyte A, intravenosamente. Nenhum cavalo recebeu fluidos orais durante a duração deste estudo. As pressões sanguíneas aumentaram em T1 no grupo HSS enquanto todos os parâmetros sanguíneos diminuíram com execepção da ureia, que permaneceu semelhante a T0. Em T2, as pressões sanguíneas para o grupo HSS eram inferiores a T1 mas superiores a T0. As concentrações de lactato diminuíram continuamente para o grupo HSS mas aumentaram em T1 para o grupo LRS. Apesar da reduzida amostra usada neste estudo, parecem existir fortes evidências dos efeitos beneficos da administração de soro salino hipertónico a cavalos com cólicas médicas. | pt_PT |
| dc.description.version | N/A | pt_PT |
| dc.identifier.citation | Stilwell, C.C.C. (2017). Effects of the administration of a bolus of 7,2% hypertonic saline solution in horses with colic, as a part of medical treatment : a preliminary study. Dissertação de mestrado. Universidade de Lisboa, Faculdade de Medicina Veterinária, Lisboa. | pt_PT |
| dc.identifier.tid | 201821923 | |
| dc.identifier.uri | http://hdl.handle.net/10400.5/14089 | |
| dc.language.iso | eng | pt_PT |
| dc.publisher | Universidade de Lisboa, Faculdade de Medicina Veterinária | pt_PT |
| dc.subject | hypertonic saline solution | en |
| dc.subject | equine colic | en |
| dc.subject | lactated Ringer’s solution | en |
| dc.subject | fluid therapy | en |
| dc.subject | soro salino hipertónico | pt_PT |
| dc.subject | cólica equina | pt_PT |
| dc.subject | lactato de Ringer | pt_PT |
| dc.subject | fluidoterapia | pt_PT |
| dc.title | Effects of the administration of a bolus of 7,2% hypertonic saline solution in horses with colic, as a part of medical treatment : a preliminary study | en |
| dc.type | master thesis | |
| dspace.entity.type | Publication | |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | masterThesis | en |
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