Repository logo
 
Publication

Spacers and valved holding chambers : the risk of switching to different chambers

2020Journal article Open access
Simple item page
dc.contributor.authorLavorini, Federico
dc.contributor.authorBarreto, Celeste
dc.contributor.authorvan Boven, Job FM
dc.contributor.authorCarroll, Will
dc.contributor.authorConway, Joy
dc.contributor.authorCostello, Richard W.
dc.contributor.authorDahl, Birthe Hellqvist
dc.contributor.authorDekhuijzen, Richard PN
dc.contributor.authorHolmes, Stephen
dc.contributor.authorLevy, Mark
dc.contributor.authorMolimard, Mathieu
dc.contributor.authorRoche, Nicholas
dc.contributor.authorRomán-Rodriguez, Miguel
dc.contributor.authorScichilone, Nicola
dc.contributor.authorScullion, Jane
dc.contributor.authorUsmani, Omar S.
dc.date.accessioned2021-04-26T11:06:14Z
dc.date.available2021-04-26T11:06:14Z
dc.date.issued2020
dc.description© 2020 The Authors. Published by Elsevier Inc. on behalf of the American Academy of Allergy, Asthma & Immunology. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)pt_PT
dc.description.abstractSpacers are pressurized metered-dose inhaler (pMDI) accessory devices developed to reduce problems of poor inhaler technique with pMDIs. Spacers that feature a 1-way inspiratory valve are termed valved holding chambers (VHCs); they act as aerosol reservoirs, allowing the user to actuate the pMDI device and then inhale the medication in a 2-step process that helps users overcome challenges in coordinating pMDI actuation with inhalation. Both spacers and VHCs have been shown to increase fine particle delivery to the lungs, decrease oropharyngeal deposition, and reduce corticosteroid-related side effects such as throat irritation, dysphonia, and oral candidiasis commonly seen with the use of pMDIs alone. Spacers and VHCs are not all the same, and also are not interchangeable: the performance may vary according to their size, shape, material of manufacture and propensity to become electrostatically charged, their mode of interface with the patient, and the presence or otherwise of valves and feedback devices. Thus, pairing of a pMDI plus a spacer or a VHC should be considered as a unique delivery system. In this Rostrum we discuss the risk potential for a patient getting switched to a spacer or VHC that delivers a reduced dose medication.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationJ Allergy Clin Immunol Pract 2020;8:1569-73pt_PT
dc.identifier.doi10.1016/j.jaip.2019.12.035pt_PT
dc.identifier.eissn2213-2201
dc.identifier.issn2213-2198
dc.identifier.urihttp://hdl.handle.net/10451/47547
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherAmerican Academy of Allergy, Asthma & Immunologypt_PT
dc.relation.publisherversionhttps://www.jaci-inpractice.orgpt_PT
dc.relation.publisherversionhttps://www.sciencedirect.com/journal/the-journal-of-allergy-and-clinical-immunology-in-practicept_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectSpacerpt_PT
dc.subjectValved holding chamberpt_PT
dc.subjectInhalerspt_PT
dc.titleSpacers and valved holding chambers : the risk of switching to different chamberspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage1573pt_PT
oaire.citation.issue5pt_PT
oaire.citation.startPage1569pt_PT
oaire.citation.titleThe Journal of Allergy and Clinical Immunology: In Practicept_PT
oaire.citation.volume8pt_PT
person.familyNameBarreto
person.givenNameCeleste
person.identifier.orcid0000-0003-3351-1862
person.identifier.scopus-author-id7003758034
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationb77db803-1483-468a-80fa-fe936b9dfa67
relation.isAuthorOfPublication.latestForDiscoveryb77db803-1483-468a-80fa-fe936b9dfa67

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Valved_holding.pdf
Size:
169.78 KB
Format:
Adobe Portable Document Format
Download

Collections

FM-CUP-Artigos em Revistas Internacionais