Publicação
Ursodeoxycholic acid modulates E2F-1 and p53 expression through a caspase-independent mechanism in transforming growth factor beta 1-induced apoptosis of rat hepatocytes
| dc.contributor.author | Sola, S | |
| dc.contributor.author | Ma, XM | |
| dc.contributor.author | Castro, RE | |
| dc.contributor.author | Kren, BT | |
| dc.contributor.author | Steer, CJ | |
| dc.contributor.author | Rodrigues, CMP | |
| dc.date.accessioned | 2015-12-30T10:17:26Z | |
| dc.date.available | 2015-12-30T10:17:26Z | |
| dc.date.issued | 2003 | |
| dc.description.abstract | Transforming growth factor beta1 (TGF-beta1)-induced hepatocyte apoptosis is associated with activation of E2F transcription factors and p53 stabilization through Mdm-2, thus potentially modulating a number of target genes. In previous studies, we have sh | |
| dc.format | application/pdf | |
| dc.identifier.citation | JOURNAL OF BIOLOGICAL CHEMISTRY. - Vol. 278, n. 49 (DEC 5 2003), p. 48831-48838 | |
| dc.identifier.doi | http://dx.doi.org/10.1074/jbc.M300468200 | |
| dc.identifier.issn | 0021-9258 | |
| dc.identifier.uri | http://hdl.handle.net/10451/21065 | |
| dc.language.iso | eng | |
| dc.publisher | AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC | |
| dc.subject | Biochemistry & Molecular Biology | |
| dc.title | Ursodeoxycholic acid modulates E2F-1 and p53 expression through a caspase-independent mechanism in transforming growth factor beta 1-induced apoptosis of rat hepatocytes | |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 48838 | por |
| oaire.citation.startPage | 48831 | por |
| oaire.citation.title | JOURNAL OF BIOLOGICAL CHEMISTRY | por |
| oaire.citation.volume | Vol. 278 | por |
| rcaap.rights | restrictedAccess | |
| rcaap.type | article |