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Single-pill combination in the management of chronic coronary syndromes: a strategy to improve treatment adherence and patient outcomes?

dc.contributor.authorPinto, Fausto J.
dc.contributor.authorPiepoli, Massimo F.
dc.contributor.authorFerrari, Roberto
dc.contributor.authorTsioufis, Konstantinos
dc.contributor.authorRosano, Giuseppe M. C.
dc.contributor.authorNedoshivin, Aleksandr
dc.contributor.authorKaski, Juan Carlos
dc.date.accessioned2023-07-18T13:05:49Z
dc.date.available2023-07-18T13:05:49Z
dc.date.issued2023
dc.description© 2023 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).pt_PT
dc.description.abstractChronic coronary syndrome (CCS) represents a major challenge for physicians, particularly in the context of an increasing aging population. Additionally, CCS is often underestimated and under-recognised, particularly in female patients. As patients are frequently affected by several chronic comorbidities requiring polypharmacy, this can have a negative impact on patients' adherence to treatment. To overcome this barrier, single-pill combination (SPC), or fixed-dose combination, therapies are already widely used in the management of conditions such as hypertension, dyslipidaemia, and diabetes mellitus. The use of SPC anti-anginal therapy deserves careful consideration, as it has the potential to substantially improve treatment adherence and clinical outcomes, along with reducing the failure of pharmacological treatment before considering other interventions in patients with CCS.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationInt J Cardiol. 2023 Aug 1;384:10-17pt_PT
dc.identifier.doi10.1016/j.ijcard.2023.04.046pt_PT
dc.identifier.eissn1874-1754
dc.identifier.issn0167-5273
dc.identifier.urihttp://hdl.handle.net/10451/58656
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relation.publisherversionhttps://www.sciencedirect.com/journal/international-journal-of-cardiologypt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectAdherencept_PT
dc.subjectAnginapt_PT
dc.subjectChronic coronary syndromept_PT
dc.subjectComorbiditiespt_PT
dc.subjectSingle-pill combinationpt_PT
dc.subjectTreatmentpt_PT
dc.titleSingle-pill combination in the management of chronic coronary syndromes: a strategy to improve treatment adherence and patient outcomes?pt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage17pt_PT
oaire.citation.startPage10pt_PT
oaire.citation.titleInternational Journal of Cardiologypt_PT
oaire.citation.volume384pt_PT
person.familyNamePinto
person.givenNameFausto J.
person.identifier1308889
person.identifier.ciencia-idC311-AEDD-6DBB
person.identifier.orcid0000-0002-8034-4529
person.identifier.ridG-9363-2015
person.identifier.scopus-author-id7102740158
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication5f44176f-69f5-482c-83cd-ab94425a6ec3
relation.isAuthorOfPublication.latestForDiscovery5f44176f-69f5-482c-83cd-ab94425a6ec3

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