Repository logo
 
Loading...
Profile Picture

Search Results

Now showing 1 - 1 of 1
  • Immunotherapy in lung cancer brain metastases
    Publication . Paisana, Eunice; Cascao, Rita; Alvoeiro, Magda; Félix, Francisco; Martins, Guilherme; Guerreiro, Carla; Roque, Rafael; Cruz, Rafael Moiteiro Da; Pacheco, Teresa; Amado, Ana Cristina; Ferro, Filipa; Lopes Machado, Andrea; Vilariça, Ana Sofia; Hasmucrai, Direndra; Alves, Paula; Faria, Claudia
    Brain metastases (BM) occur frequently in lung cancer, particularly in non-small cell lung cancer (NSCLC) patients and remain a significant cause of morbidity and mortality. Standard therapies have limited efficacy due to poor crossing of the blood-brain barrier and the distinct features between BM and the primary tumor. This review explores the immune landscape of brain metastatic disease, emerging immunotherapeutic strategies, and promising biomarkers in NSCLC patients.