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Browsing by Author "Silva, Marcelo"

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  • Advancing the global public health agenda for NAFLD: a consensus statement
    Publication . Lazarus, Jeffrey V.; Mark, Henry E.; Anstee, Quentin M.; Arab, Juan Pablo; Batterham, Rachel L.; Castera, Laurent; Cortez-Pinto, Helena; Crespo, Javier; Cusi, Kenneth; Dirac, M. Ashworth; Francque, Sven; Hickman, Ingrid J.; Hocking, Samantha L.; Hunyady, Bela; Idilman, Ramazan; Isakov, Vasily A.; Jamal, Mohammad H.; Jepsen, Peter; Iskandar, Natacha Jreige; Song, Myeong Jun; Sudhamshu, K. C.; George, Jacob; Kakizaki, Satoru; Kalamitsis, George; Kanwal, Fasiha; Kao, Jia-Horng; Kaplan, Lee; Kawaguchi, Takumi; Khader, Yousef; Kim, Seung Up; Kodjoh, Nicolas; Koek, Ger; Hagström, Hannes; Koike, Kazuhiko; Komas, Narcisse Patrice; Korenjak, Marko; Kugelmas, Marcelo; Labidi, Asma; Lange, Naomi F.; Lavine, Joel E.; Lazo, Mariana; Lee, Nancy; Lesmana, Cosmas Rinaldi A.; Huang, Terry T.-K.; Liu, Chun-Jen; Long, Michelle T.; Lopez-Jaramillo, Patricio; Malekzadeh, Reza; Mahtab, Mamun Al; Marchesini, Giulio; Marinho, Rui; Vázquez, Sophia E. Martínez; Mateva, Lyudmila; Nlombi, Charles Mbendi; Ismail, Mona H.; Melin, Pascal; Mikolasevic, Ivana; Milovanovic, Tamara; Musso, Carla; Nakajima, Atsushi; Nava, Edna; Nersesov, Alexander V.; Nikolova, Dafina; Norris, Suzanne; Novak, Katja; Kautz, Achim; Oben, Jude; Ong, Janus P.; Onyekwere, Charles; Papatheodoridis, George; Paruk, Imran; Patel, Keyur; Macedo, M. Paula; Penha-Gonçalves, Carlos; Figueroa, Marlene Pérez; Hofmann, Wolf Peter; Sarin, Shiv Kumar; Petta, Salvatore; de Oliveira, Claudia Pinto Marques Souza; Puri, Puneet; Pan, Calvin Q.; Rac, Marek; Ralston, Johanna; Ramji, Alnoor; Razavi, Homie; Alvares-da-Silva, Mario Reis; Roberts, Stuart; Loomba, Rohit; Roden, Michael; Rose, Tamsin; Rouabhia, Samir; Rovere-Querini, Patrizia; Rowe, Ian A.; Sadirova, Shakhlo; Salupere, Riina; Saparbu, Tobokalova; Sayegh, Raymond; Sebastiani, Giada; Miller, Veronica; Seki, Yosuke; Selmo, Josefina; Serme, Abdel Karim; Shaw, Jonathan E.; Shenoy, Thrivikrama; Sheron, Nick; Shibolet, Oren; Silva, Marcelo; Skrypnyk, Igor; Socha, Piotr; Newsome, Philip N.; Soriano, Joan; Spearman, C. Wendy; Sridharan, Kannan; Suárez, Juan José; Sheriff, Dhastagir Sultan; Sung, Ki-Chul; Swain, Mark; Tacke, Frank; Taheri, Shahrad; Tan, Soek-Siam; Ninburg, Michael; Tapper, Elliot B.; Yki-Järvinen, Hannele; Thiele, Maja; Shawa, Isaac Thom; Tolmane, Ieva; Torres, Esther A.; Trauner, Michael; Treeprasertsuk, Sombat; Turcanu, Adela; Valantinas, Jonas; Ocama, Ponsiano; Vesterhus, Mette; Waked, Imam; Wild, Sarah H.; Willemse, Jose; Wong, Robert J.; Xanthakos, Stavra; Young, Dan Yock; Yu, Ming-Lung; Zheng, Kenneth I.; Zeybel, Mudjat; Ratziu, Vlad; Zheng, Ming-Hua; Rinella, Mary; Romero, Diana; Romero-Gómez, Manuel; Schattenberg, Jörn M.; Tsochatzis, Emmanuel A.; Valenti, Luca; Wong, Vincent Wai-Sun; Yilmaz, Yusuf; Younossi, Zobair M.; Zelber-Sagi, Shira; Åberg, Fredrik; Adams, Leon; Khatry, Maryam Salem Al; Naamani, Khalid Al; Murillo, Omar Alfaro; Allen, Alina M.; Alnaser, Faisal; Alqahtani, Saleh A.; Alswat, Khalid; Alvaro, Domenico; Andrade, Raúl J.; Arrese, Marco; Awuku, Yaw Asante; Ayesha, Motala; Baatarkhuu, Oidov; Bakieva, Shokhista; Basu, Rita; Bataller, Ramon; Bedri, Shahinaz; Bosi, Emanuele; Bourliere, Marc; Bruha, Radan; Bugianesi, Elisabetta; Burra, Patrizia; Buti, Maria; Byrne, Christopher D.; Calleja, Jose Luis; Carrieri, Patrizia; Carter, Flloyd; Fernandez, Marlen Ivon Castellanos; Castillo-Lopez, Gabriela; Castro-Narro, Graciela E.; Chan, Henry Lik Yuen; Chan, Wah-Kheong; Chang, Yoosoo; Colombo, Massimo; Coppell, Kirsten J.; Corey, Kathleen; Craxi, Antonio; Cryer, Donna; Dassanayake, Anuradha; Martins, Antonieta de Ascenção Soares; de Ledinghen, Victor; DelPrato, Stefano; Demaio, Alessandro; Desalegn, Hailemichael; Dillon, John; Duseja, Ajay; Dorairaj, Prabhakaran; Ekstedt, Mattias; El Kassas, Mohamed; Elsanousi, Osama M.; Esmat, Gamal; Fan, Jian-Gao; Farpour-Lambert, Nathalie; Flisiak, Robert; Fouad, Yasser; Fuchs, Michael; Gani, Rino A.; Gerber, Lynn; Ghazinyan, Hasmik; Gheorghe, Liana; Goh, George Boon-Bee; Grønbæk, Henning; Gulnara, Aghayeva; Hamid, Saeed; Hebditch, Vanessa
    Non-alcoholic fatty liver disease (NAFLD) is a potentially serious liver disease that affects approximately one-quarter of the global adult population, causing a substantial burden of ill health with wide-ranging social and economic implications. It is a multisystem disease and is considered the hepatic component of metabolic syndrome. Unlike other highly prevalent conditions, NAFLD has received little attention from the global public health community. Health system and public health responses to NAFLD have been weak and fragmented, and, despite its pervasiveness, NAFLD is largely unknown outside hepatology and gastroenterology. There is only a nascent global public health movement addressing NAFLD, and the disease is absent from nearly all national and international strategies and policies for non-communicable diseases, including obesity. In this global Delphi study, a multidisciplinary group of experts developed consensus statements and recommendations, which a larger group of collaborators reviewed over three rounds until consensus was achieved. The resulting consensus statements and recommendations address a broad range of topics - from epidemiology, awareness, care and treatment to public health policies and leadership - that have general relevance for policy-makers, health-care practitioners, civil society groups, research institutions and affected populations. These recommendations should provide a strong foundation for a comprehensive public health response to NAFLD.
    2021Journal article Restricted access Show more
  • Sett Use, Density and Breeding Phenology of Badgers in Mediterranean Agro-Sylvo-Pastoral Systems
    Publication . Silva, Marcelo; Rosalino, L. M.; Alcobia, Sandra; Santos-Reis, Margarida
    Carnivores social organization varies widely, from strongly social to solitary predators. European badgers are facultative social carnivores that also shows a geographical variation in social structure. These patterns derive mainly from central/west European regions, with an underrepresentation of Mediterranean populations that face different conservation challenges, especially regarding group composition, sett use patterns and breeding phenology. We addressed these traits topics for a population inhabiting a Portuguese agro-silvo-pastoral system. Based on monthly monitoring of 34 setts and continuous camera-trapping surveys of 12, we showed that setts surrounded by diversified vegetation and located in sandy sites are more used, a pattern probably linked to food availability and ease of sett excavation and maintenance, respectively. Badgers followed a general pattern regarding group size (2–4 adults), but showed an intermediate population density (0.49–0.73 badgers/km2), with values higher than those estimated for other Mediterranean environments, but lower than for central-western populations. This, together with the breeding (November/January) and cub emergence (1.8 cubs/sett; March/April) periods, indicates an ecological adaptation to the landscape context, where human-related resources and mild environmental conditions allow badger to reach higher densities than in many southern populations, and to reproduce earlier than their northern counterparts.
    2021-09Journal article Open access Show more
  • The global NAFLD policy review and preparedness index: are countries ready to address this silent public health challenge?
    Publication . Lazarus, Jeffrey V.; Mark, Henry E.; Villota-Rivas, Marcela; Palayew, Adam; Carrieri, Patrizia; Colombo, Massimo; Ekstedt, Mattias; Esmat, Gamal; George, Jacob; Marchesini, Giulio; Novak, Katja; Ocama, Ponsiano; Ratziu, Vlad; Razavi, Homie; Romero-Gómez, Manuel; Silva, Marcelo; Spearman, C. Wendy; Tacke, Frank; Tsochatzis, Emmanuel A.; Yilmaz, Yusuf; Younossi, Zobair M.; Wong, Vincent W.-S.; Zelber-Sagi, Shira; Cortez-Pinto, Helena; Anstee, Quentin M.; Rouabhia, Samir; Ghazinyan, Hasmik; Iskandar, Natacha Jreige; Trauner, Michael; Aghayeva, Gulnara; Carter, Flloyd; Sridharan, Kannan; Al Mahtab, Mamun; Francque, Sven; Kodjoh, Nicolas; Camacho, Ruben Muñoz; Anderson, Motswedi; Marques Souza de Oliveira, Claudia Pinto; Mateva, Lyudmila; Serme, Abdel Karim; Soares Martins, Antonieta A.; Swain, Mark G.; Komas, Narcisse Patrice; Zheng, Ming-Hua; Jaramillo, Patricio Lopez; Murillo, Omar Alfaro; Mikolasevic, Ivana; Vounou, Emmelia; Brůha, Radan; Nlombi, Charles Mbendi; Thiele, Maja; Perez, Marlene; Suárez M, Juan José; Waked, Imam; Salupere, Riina; Desalegn, Hailemichael; Yki-Järvinen, Hannele; Tsertsvadze, Tengiz; Sharvadze, Lali; Butsashvili, Maia; Awuku, Yaw Asante; Papatheodoridis, Georgios; Hunyady, Bela; Bjornsson, Einar Stefan; Duseja, Ajay; Lesmana, Cosmas Rinaldi A.; Malekzadeh, Reza; Norris, Suzanne; Koike, Kazuhiko; Nersesov, Alexander V.; Ochwoto, Missiani; Jamal, Mohammad; Saparbu, Tobokalova; Tolmane, Ieva; Sayegh, Raymond; Sheriff, Dhastagir Sultan; Valantinas, Jonas; Weber, Joseph; Shawa, Isaac Thom; Tan, Soek-Siam; Martínez Vázquez, Sophia E.; Baatarkhuu, Oidov; Lkhagvaa, Undram; Jadamba, Tsolmon; Mohammed, Tahiri; Sudhamshu, K.C; Coppell, Kirsten; Onyekwere, Charles; Nikolova, Dafina; Vesterhus, Mette; Al-Naamani, Khalid; Hamid, Saeed; Méndez, Juan Paredes; Cabrera Cabrejos, María Cecilia; Flisiak, Robert; Torres, Esther A.; Taheri, Shahrad; Sung, Ki-Chul; Adela, Turcanu; Gheorghe, Liana; Sanai, Faisal M.; Milovanovic, Tamara; Bee Goh, George Boon; Rac, Marek; Dassanayake, Anuradha; Osama, Shahinaz Bedri; Elsanousi, M.; Dufour, Jean-François; Kao, Jia-Horng; Saidi, Dilshod; Treeprasertsuk, Sombat; Koek, Ger; Labidi, Asma; Skrypnyk, Igor; AlKhatry, Maryam Salem; Sadirova, Shakhlo; Bakieva, Shokhista; Sinkala, Edford
    Background & aims: Non-alcoholic fatty liver disease (NAFLD) is a highly prevalent, yet largely underappreciated liver condition which is closely associated with obesity and metabolic disease. Despite affecting an estimated 1 in 4 adults globally, NAFLD is largely absent on national and global health agendas. Methods: We collected data from 102 countries, accounting for 86% of the world population, on NAFLD policies, guidelines, civil society engagement, clinical management, and epidemiologic data. A preparedness index was developed by coding questions into 6 domains (policies, guidelines, civil awareness, epidemiology and data, NAFLD detection, and NAFLD care management) and categorising the responses as high, medium, and low; a multiple correspondence analysis was then applied. Results: The highest scoring countries were India (42.7) and the United Kingdom (40.0), with 32 countries (31%) scoring zero out of 100. For 5 of the domains a minority of countries were categorised as high-level while the majority were categorised as low-level. No country had a national or sub-national strategy for NAFLD and <2% of the different strategies for related conditions included any mention of NAFLD. National NAFLD clinical guidelines were present in only 32 countries. Conclusions: Although NAFLD is a pressing public health problem, no country was found to be well prepared to address it. There is a pressing need for strategies to address NAFLD at national and global levels. Lay summary: Around a third of the countries scored a zero on the NAFLD policy preparedness index, with no country scoring over 50/100. Although NAFLD is a pressing public health problem, a comprehensive public health response is lacking in all 102 countries. Policies and strategies to address NAFLD at the national and global levels are urgently needed.
    2022Journal article Open access Show more