Browsing by Author "Kuehnel, Mark"
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- Anti-inflammatory effects of phosphatidylcholinePublication . Treede, Irina; Braun, Annika; Sparla, Richard; Kuehnel, Mark; Giese, Thomas; Turner, Jerrold R.; Anes, Elsa; Kulaksiz, Hasan; Fuellekrug, Joachim; Stremmel, Wolfgang; Griffiths, Gareth; Ehehalt, RobertWe recently showed that mucus from patients with ulcerative colitis, a chronic inflammatory disorder of the colon, is characterized by a low level of phosphatidylcholine (PC) while clinical studies reveal that therapeutic addition of PC using slow release
- Modelling phagosomal lipid networks that regulate actin assemblyPublication . Kuehnel, Mark; Mayorga, Luis S.; Dandekar, Thomas; Thakar, Juilee; Schwarz, Roland; Anes, Elsa; Griffiths, Gareth; Reich, JensBackground: When purified phagosomes are incubated in the presence of actin under appropriate conditions, microfilaments start growing from the membrane in a process that is affected by ATP and the lipid composition of the membrane. Isolated phagosomes ar. - DFG [Da 208/7-2, TR34]; BMBF ; Irvington Institute CRI ; FEDER [POCI, PPCDT/BIA- BCM/55327/2004]; Alexander von Humboldt Foundation ; CONICET. - We thank J. Brouwers and B. Helms from Univ. Utrecht, Holland for communicating unpublished data on lipids in LBP phagosomes. This work was generously supported by DFG (Da 208/7-2; TR34), BMBF (Hepatosys, TD and JR; PathogenomikPlus, RS), the Irvington In