Browsing by Author "Brizio, A"
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- A new integron-mediated rifampin resistance in a clinical isolate of Pseudomonas aeruginosa, from a Portuguese hospitalPublication . Duarte, A; Brizio, A; Conceição, T; Ferreira, T
- Class 1 and class 3 integrons among Klebsiella oxytoca in a paediatric hospitalPublication . Conceicao, T; Brizio, A; Barros, R; Duarte, A
- Emergence of CTX-M-15 beta-lactamase in clinical isolates of Enterobacteriaceae from three hospitals in LisbonPublication . Duarte, A; Conceicao, T; Brizio, A; Vasco, S; Serejo, M
- Escherichia coli producing TEM 1b generate incorrect extrapolation by VITEK2 expert systemPublication . Brizio, A; Fernandes, AT; Canas, E; Ferreira, T; Duarte, A
- First description of CTX-M-15-producing Klebsiella pneumoniae in PortugalPublication . Conceicao, T; Brizio, A; Duarte, A; Lito, LM; Cristino, JM; Salgado, MJ
- First isolation of bla(VIM-2) in Klebsiella oxytoca clinical isolates from PortugalPublication . Conceicao, T; Brizio, A; Duarte, A; Barros, R
- High-level expression of IMP-5 carbapenemase owing to point mutation in the -35 promoter region of class 1 integron among Pseudomonas aeruginosa clinical isolatesPublication . Brizio, A; Conceicao, T; Pimentel, M; Da Silva, G; Duarte, AEight strains of Pseudomonas aeruginosa producing IMP-5 carbapenemases were collected from three Portuguese hospitals. All isolates were epidemiologically unrelated. The bla(IMP-5) gene was inserted into a class I integron previously reported in Acinetobacter baumannii 65FFC. Expression of the the blaIMP-5 gene in P aeruginosa has been shown to be driven by the P, promoter [TTGATA] in which the cytosine was replaced by thymine, which caused an increase in transcription of blaIMP-5 that was confirmed by site-directed mutagenesis. The minimum inhibitory concentrations (MICs) of imipenem for Escherichia coli pGMLA-1 (the recombinant front A. baumannii 65FFC) and E. coli pATG-2 (the recombinant from P. aeruginosa isolates) were 0.5 mg/L and 32 mg/L, respectively. This study reports the spread of a class 1 integron In76 with a new point mutation in the P-1 promoter sequence leading to overproduction of INIP-5. (c) 2005 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved.
- Spread of In58 containing blavim-2 among Pseudomonas aeruginosaPublication . Brizio, A; Silva, A; Canas, E; Ferreira, T; Lito, LM; Cristino, JMelo; Salgado, MJ; Duarte, A
- Transduction of imipenem resistance by bacteriophages carried by Pseudomonas aeruginosa clinical isolatesPublication . Brizio, A; Silva, GDa; Duarte, A; Pimentel, M