Fortunato, MileneLy, Chi-PhongSiopa, FilipaAfonso, Carlos2023-09-142023-09-142019-08-05Fortunato MAG, Ly C-P, Siopa F, Afonso CAM. Process Intensification for the Synthesis of 6-Allyl-6-azabicyclo[3.1.0]hex-3-en-2-ol from 1-Allylpyridinium Salt Using a Continuous UV-Light Photoflow Approach. Methods and Protocols [Internet]. 2019 Aug 5;2(3):67. Available from: http://dx.doi.org/10.3390/mps2030067http://hdl.handle.net/10451/59299© 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).A new home-made UV photochemical reactor (95 cm of irradiation zone) consisting of a 12 parallel quartz tubes flow reactor, PQT6 (95 cm under irradiation and an internal diameter of 0.6 cm) was assembled to perform photochemical transformations in continuous-flow. PQT6 was evaluated for the photoreaction of 1-allylpyridinium bromide (1a) to 6-allyl-6-azabicyclo[3.1.0]hex-3-en-2-ol (2a), in a continuous process. This technology provides reduced reaction times, continuous production of 2a, and a productivity of 129 mg h−1, corresponding to 1.94 g of isolated 2a after 15 h of irradiation.engflow reactionphotochemistrybicyclic aziridinejournal article2023-02-23cv-prod-110236910.3390/mps2030067