Rodrigues, CMPSola, SBrites, D2015-12-302015-12-302002HEPATOLOGY. - Vol. 35, n. 5 (MAY 2002), p. 1186-11950270-9139http://hdl.handle.net/10451/21054Increased levels of unconjugated bilirubin, the end-product of heme catabolism, are detrimental to the central nervous system. To examine the role of apoptosis in bilirubin-induced toxicity and to characterize the biochemical pathway of cell death, we expapplication/pdfengGastroenterology & HepatologyBilirubin induces apoptosis via the mitochondrial pathway in developing rat brain neuronsjournal articlehttp://dx.doi.org/10.1053/jhep.2002.32967