Apoptosis and impairment of neurite network by short exposure of immature rat cortical neurons to unconjugated bilirubin increase with cell differentiation and are additionally enhanced by an inflammatory stimulus

Falcao, Ana S.Silva, Rui F. M.Pancadas, SergioFernandes, AdelaideBrito, Maria A.Brites, Dora2015-12-302015-12-302007JOURNAL OF NEUROSCIENCE RESEARCH. - Vol. 85, n. 6 (MAY 1 2007), p. 1229-12390360-4012http://hdl.handle.net/10451/21566Nerve cell injury induced by unconjugated bilirubin (UCB) has been implicated in brain damage during severe neonatal hyperbilirubinemia, although the molecular mechanisms underlying UCB neurotoxicity are still not clarified. It has been suggested recentlyapplication/pdfengNeurosciencesApoptosis and impairment of neurite network by short exposure of immature rat cortical neurons to unconjugated bilirubin increase with cell differentiation and are additionally enhanced by an inflammatory stimulusjournal articlehttp://dx.doi.org/10.1002/jnr.21227