Couto, Francisco M.Silva, Mário J.Coutinho, Pedro M.2009-02-102014-11-142009-02-102014-11-142003-11http://hdl.handle.net/10451/14233http://repositorio.ul.pt/handle/10455/2935Sequence similarity is a common technique to compare gene-products. However, many applications need to compare gene-products based on what they do, not how they are. Most gene-products are being annotated with terms describing their biological function. These terms are defined in biological ontologies. This makes it possible to implement similarity measures between gene-products based on their behavior. We define FuSSiMeG, a functional similarity measure between gene-products that compares the semantic similarity between the terms in their annotations. Software available from http://xldb.fc.ul.pt/rebil/ssm/porreport