Martins, João MartinFraga, M.Miguens, J.Tortosa, F.Marques, BárbaraSousa, A. D.2021-07-302021-07-302017-12Andrologia. 2017 Dec;49(10).0303-4569http://hdl.handle.net/10451/49236© 2017 Blackwell Verlag GmbHDisorders of sex development generally present in the neonatal period with ambiguity of external genitalia. We report a very old male patient presenting at 75 years because of panhypopituitarism and a large nonsecreting pituitary macroadenoma secondary to long-standing primary hypogonadism due to 46,XX sex reversal disorder now first diagnosed. Sex development disorders may go unrecognised for the entire life span, despite infertility and long-standing primary gonadic failure may lead to uncommon complications.engNeonatal hypogonadismPituitary gonadotrophic adenomaSex reversaljournal article10.1111/and.128311439-0272