Attenuation of HIV-1 replication in primary human cells with a designed zinc finger transcription factor

Segal, DJGoncalves, JEberhardy, SSwan, CHTorbett, BELi, XLBarbas, CF2015-12-302015-12-302004JOURNAL OF BIOLOGICAL CHEMISTRY. - Vol. 279, n. 15 (APR 9 2004), p. 14509-145190021-9258http://hdl.handle.net/10451/21599Small molecule inhibitors of human immunodeficiency virus, type 1 (HIV-1) have been extremely successful but are associated with a myriad of undesirable effects and require lifelong daily dosing. In this study we explore an alternative approach, that of iapplication/pdfengBiochemistry & Molecular BiologyAttenuation of HIV-1 replication in primary human cells with a designed zinc finger transcription factorjournal articlehttp://dx.doi.org/10.1074/jbc.M400349200