HIV-1 Vif can directly inhibit apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3G-mediated cytidine deamination by using a single amino acid interaction and without protein degradation

Santa-Marta, Mda Silva, FAFonseca, AMGoncalves, J2015-12-302015-12-302005JOURNAL OF BIOLOGICAL CHEMISTRY. - Vol. 280, n. 10 (2005), p. 8765-87750021-9258http://hdl.handle.net/10451/21603The human apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3G (APOBEC3G), also known as CEM-15, is a host-cell factor involved in innate resistance to retroviral infection. HIV-1 viral infectivity factor (Vif) protein was shown to protect tapplication/pdfengBiochemistry & Molecular BiologyHIV-1 Vif can directly inhibit apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3G-mediated cytidine deamination by using a single amino acid interaction and without protein degradationjournal articlehttp://dx.doi.org/10.1074/jbc.M409309200