Effects of omega-3 and-6 fatty acids on Mycobacterium tuberculosis in macrophages and in mice

Jordao, LuisaLengeling, AndreasBordat, YannBoudou, FredericGicquel, BrigitteNeyrolles, OlivierBecker, Pablo D.Guzman, Carlos A.Griffiths, GarethAnes, Elsa2015-12-302015-12-302008MICROBES AND INFECTION. - Vol. 10, n. 41609 (OCT 2008), p. 1379-13861286-4579http://hdl.handle.net/10451/21583We recently showed that treatment of macrophages prior to Mycobacterium tuberculosis infection with the pro-inflammatory omega-6 lipid, arachidonic acid (AA) enhanced bacterial killing whereas the anti - inflammatory, omega-3 lipid eicosapentaenoic acid (. - FCT ; FEDER [POCI/BIA-BCM/55327/2004, SFRWBD/14284/2003]. - We thank Cecilia Rodrigues, Maximilliano Gutierrez, Luis Mayorga and Sabrina Marion for their constructive support and discussion. This work was financed by FCT with co-participation of FEDER (POCI/BIA-BCM/55327/2004 and SFRWBD/14284/2003).application/pdfengImmunologyMicrobiologyVirologyEffects of omega-3 and-6 fatty acids on Mycobacterium tuberculosis in macrophages and in micejournal articlehttp://dx.doi.org/10.1016/j.micinf.2008.08.004