Grinfeld, RenataMeira e Cruz, Miguel2019-10-182019-10-182019Seizure. 2019 Jul;69:116-1171059-1311http://hdl.handle.net/10451/39890© 2019 Published by Elsevier Ltd on behalf of British Epilepsy Association.Focal impaired awareness seizure (FIAS) is a clinical phenomenon with a prevalence of 0.8% that manifests as epileptic discharges commonly located in the amygdala-hippocampal complex. It can cause visual delusions and olfactory, auditory, or affective hallucinations. Obstructive sleep apnea (OSA) is common in patients with epilepsy. Despite their limitations, some studies have revealed an important relationship between OSA and refractory epileptic seizures (RES), as well as between OSA improvement and a corresponding RES improvement with adequate continuous positive airway pressure (CPAP) Mandibular advancement devices (MADs) have been proven to be effective in patients with OSA. Although typically contraindicated in seizure disorders, the efficacy of MADs in the treatment of OSA-associated epileptic events was reported by Fenton JE et al. recently, suggesting its relevance in specific circumstances such as the comorbidity of OSA and epilepsy. In this report, we present a clinical case of a patient diagnosed with FIAS and moderate OSA who was treated with MADs.engjournal article10.1016/j.seizure.2019.04.012