Kaur, HardeepMachado, Martade Kock, CarmenSmith, PeterChibale, KellyPrudêncio, MiguelSingh, Kamaljit2022-04-202022-04-202015Eur J Med Chem. 2015 Aug 28;101:266-2730223-5234http://hdl.handle.net/10451/52462© 2015 Elsevier Masson SAS. All rights reserved.A series of novel pyrimidine-primaquine hybrids were synthesized and their effectiveness against the blood and liver stages of malaria parasites was evaluated. The hybrids displayed enhanced liver stage in vitro activity against P. berghei liver stage infection.engAntiplasmodial agentsBlood stage activityHybrid drugsLiver stage activityPrimaquinePyrimidinePrimaquine–pyrimidine hybrids: synthesis and dual-stage antiplasmodial activityjournal article10.1016/j.ejmech.2015.06.0451768-3254