Ângelo, DavidMorouço, PedroMonje Gil, FlorencioMónico, LiseteGonzález-Gárcia, RaúlSousa, RitaLucas Neto, LiaCaldeira, InêsSmith, MargaretSmith, SusanSanz, DavidAbade dos Santos, FábioPinho, MárioCarrapiço, BelmiraCavaco, SandraMoura, CarlaAlves, NunoSalvado, FranciscoLittle, Christopher2021-04-122021-04-122018Journal of Cranio-Maxillofacial Surgery, Volume 46, Issue 4, 2018, Pages 688-6961010-5182http://hdl.handle.net/10451/47343© 2018 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.The role of temporomandibular joint (TMJ) surgery is not well defined due to a lack of quality randomized controlled clinical trials, comparing different TMJ surgical treatments with medical and placebo interventions. The temporomandibular joint interposal study (TEMPOJIMS) is a rigorous preclinical trial divided in 2 phases. In phase 1 the authors investigated the role of the TMJ disc and in phase 2 the authors evaluated 3 different interposal materials. The present work of TEMPOJIMS - phase 1, aims to evaluate histopathologic and imaging changes of bilateral discectomy and discopexy in Black Merino sheep TMJ, using a high-quality trial following the ARRIVE guidelines.engAnimalsBody weightFemaleMandibular condyleSheepTemporomandibular jointTemporomandibular joint discTomography, X-Ray computedjournal article10.1016/j.jcms.2018.01.0061878-4119