Simões, Maria de FátimaRijo, PatríciaDuarte, AidaBarbosa, DianaMatias, DiogoDelgado, JoanaCirilo, NádiaRodríguez, Benjamín2011-08-222011-08-222010Phytochemistry Letters. December 2010, 3(4) 221-2251874-3900http://dx.doi.org/10.1016/j.phytol.2010.08.002http://hdl.handle.net/10451/3937Two new diterpenoids, ent-7α-acetoxy-15-beyeren-18-oic acid and (13S,15S)-6β,7α,12α,19-tetrahydroxy-13β,16-cyclo-8-abietene-11,14-dione, have been isolated from Plectranthus saccatus and Plectranthus porcatus, respectively, and their structures were established by 1D and 2D NMR spectroscopic studies. The new diterpenes showed no activity against Gram-negative bacteria and Candida albicans (yeast strain). Among Gram-positive bacteria, the lower MIC value was 62.50 μg/ml for the abietane derivative against Staphylococcus aureus ATCC 6538.engPlectranthus saccatusPlectranthus porcatusLamiaceaeDiterpenesBeyerane13,16-CycloabietaneBiological activityjournal article