Silva, MFBRuiter, JPNOvermars, HBootsma, AHvan Gennip, AHJakobs, CDuran, Mde Alemida, ITWanders, RJA2015-12-302015-12-302002BIOCHEMICAL JOURNAL. - Vol. 362, Part 3 (2002), p. 755-7600264-6021http://hdl.handle.net/10451/21333The beta-oxidation of valproic acid (VPA; 2-n-propylpentanoic acid) was investigated in vitro in intact rat liver mitochondria incubated with H-3-labelled VPA. The metabolism of [4,5-H-3(2)]VPA and [2-H-3]VPA was studied by analysing the different acyl-Coapplication/pdfengBiochemistry & Molecular BiologyComplete beta-oxidation of valproatecleavage of 3-oxovalproyl-CoA by a mitochondrial 3-oxoacyl-CoA thiolasejournal article